Abstract
A simple and efficient process for the preparation of 87Y/87mSr generator with adsorption chromatography on α-Fe2O3 was developed. A 0.25 g pallet of natural SrCl2 was employed as a solid target which was irradiated at INER TR30/15 cyclotron. After irradiation the target was dissolved into a saline solution and adjusted with HCl/NaOH to a pH of 6.3. This solution was then passed directly through the column (1 cm⊘×4 cm), loaded with appropriate amounts of α-Fe2O3, at a flowrate of 1.0 ml/min for adsorption of 87Y. Nonradioactive Sr was unadsorbed and washed out from the column. Above 90% of the available 87mSr with a 87Y breakthrough less than 10−3% could be obtained with 10 ml of 0.9% saline solution per elution from the generator system. The chemical contaminants of Fe and Sr in the eluates were found below 0.04 and 0.1 ppm, respectively.
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Cheng, WL., Lo, AR. A Simple and Rapid Method for the Preparation of 87Y/87mSr Generator. Journal of Radioanalytical and Nuclear Chemistry 245, 31–36 (2000). https://doi.org/10.1023/A:1006770123421
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DOI: https://doi.org/10.1023/A:1006770123421