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INAA Applied to Halogen (Br and I) Stability in Long-Term Storage of Lyophilized Biological Materials

  • V. Zaichick
  • S. Zaichick
Article

Abstract

Instrumental neutron activation analysis (INAA) was used to determine the Br and I concentration in the same ten lyophilized and homogenized human thyroid samples prior and after a 20-year storage at room temperature. It was found that long-term storage had no effect on the iodine content. At the same time, the bromine content was about 2-fold lower (p<0.01). It was assumed that possible losses of other halogens can occur under long-term storage of lyophilized biological materials at room temperature.

Keywords

Physical Chemistry Inorganic Chemistry Iodine Activation Analysis Bromine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    M. Rossbach, D. J. Schladot, P. Ostapczuk (Eds), Specimen Banking. Springer-Verlag, Berlin-Heidelberg, 1992.Google Scholar
  2. 2.
    R. Zeisler, B. J. Koster, S. A. Wise, in: Specimen Banking, Springer-Verlag, Berlin-Heidelberg, 1992, p. 37.Google Scholar
  3. 3.
    E. L. Lakomaa, H. Mussalo-Rauhamaa, S. Salmela, J. Trace Elem. Electrolytes Health Dis., 2 (1988) 37.PubMedGoogle Scholar
  4. 4.
    G. W. Comstock, A. J. Albert, K. J. Helzlsonerr, Clin. Chem., 39 (1993) 1075.PubMedGoogle Scholar
  5. 5.
    W. J. Driskell, A. D. Lackey, J. S. Hewett, M. M. Bashor, Clin. Chem., 31 (1985) 871.PubMedGoogle Scholar
  6. 6.
    E. W. Gunter, W. J. Driskell, P. R. Yeager, Clin. Chem. Acta, 175 (1988) 329.Google Scholar
  7. 7.
    N. E. Craft, E. D. Brown, J. C. Smith Jr., Clin. Chem., 34 (1988) 44.PubMedGoogle Scholar
  8. 8.
    G. W. Comstock, E. P. Norkus, S. C. Hoffman, M.-W. Xu, K. J. Helzlsoner, Cancer Epidemiology, Biomarkers, and Prevention, 4 (1995) 505.Google Scholar
  9. 9.
    R. Zeisler, R. R. Greenberg, S. F. Stone, T. M. Sullivan, Fresenius J. Anal. Chem., 332 (1988) 612.Google Scholar
  10. 10.
    M. Rossbach, H. Emons, A. Groemping, P. Ostapczuk, D. J. Schladot, in: Intern. Symp. on Harmonization of Health-Related Environmental Measurements Using Nuclear and Isotopic Techniques, IAEA-SM-34, 1996, p. 55.Google Scholar
  11. 11.
    R. Ch. Daniel, P. Lischer, J. Paul, A. Clement, G. Theiller, in: 7th Intern. Symp. on Biological and Environmental Reference Materials, BERM-7, 1997, p. 1/12.Google Scholar
  12. 12.
    G. V. Iyengar, in: Modern Trends in Activation Analysis, MTAA-7, Risø National Laboratory, Roskilde, 1986, p. 107.Google Scholar
  13. 13.
    K. Byrialsen, J. Kristiansen, J. M. Christensen, in: 7th Intern. Symp. on Biological and Environmental Reference Materials, BERM-7, 1997, p. 6B/6.Google Scholar
  14. 14.
    V. Zaichick, Y. Choporov, J. Radioanal. Nucl. Chem., 207 (1996) 153.Google Scholar
  15. 15.
    G. V. Iyengar, W. E. Kollmer, H. J. M. Bowen, The Elemental Composition of Human Tissues and Body Fluids, Verlag Chemie, Weinhein-New York, 1978.Google Scholar
  16. 16.
    K. Maeda, Y. Yokode, Y. Sasa, H. Kusuyama, M. Uda, Nucl. Instrum. Meth., B22 (1987) 188.Google Scholar
  17. 17.
    S. Ohno, Analyst, 96 (1971) 423.PubMedGoogle Scholar
  18. 18.
    I. Akabane, S. Shimizu, T. Cho, G. V. Iyengar, in: 7th Intern. Symp. on Biological and Environmental Reference Materials, BERM-7, 1997, p. I/18.Google Scholar
  19. 19.
    F. C. Hickey, G. L. Brownell, J. Clin. Endocrinol., 14 (1954) 1423.Google Scholar
  20. 20.
    M. Ermans, J. Kinthaert, M. Camus, J. Clin. Endocrinol., 28 (1968) 1307.Google Scholar
  21. 21.
    W. Buchberger, W. Holler, K. Winsauer, J. Trace Elem. Electrolytes Health Dis., 4 (1990) 25.PubMedGoogle Scholar

Copyright information

© Akadémiai Kradó, Budapest 2000

Authors and Affiliations

  • V. Zaichick
    • 1
  • S. Zaichick
    • 2
  1. 1.Medical Radiological Research CentreObninskRussia
  2. 2.Russian State Medical UniversityMoscowRussia

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