Abstract
The genetic control of resistance to RSV (RAV-50) in chick embryos inoculated via the chorioallantoic membrane route was studied in three breeds of chickens. The relative susceptibility to subgroup D infection was 0.01, 0.02 and 0.003 in broilers, White Leghorns and Bantam×Australorp crosses, respectively. The distribution pattern of putative dr gene frequencies were 0.80, 0.68 and 0.90, respectively, in the same three breeds. Liver tumours resulting from the virus infection were observed in a very few birds about 28 days after hatching.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
REFERENCES
Anon, 1990. Annual Report, (Project Directorate on Poultry, Hyderabad)
Bauer, H. and Graf, T., 1969. Evidence for the possible existence of two envelope antigenic determinants and corresponding cell receptors for avian tumour viruses. Virology, 37, 157-161
Crittenden, L.B. and Motta, J.V., 1969. A survey of genetic resistance to leukosis-sarcoma viruses in commercial stocks of chickens. Poultry Science, 48, 1751-1757
Crittenden, L.B. and Okazaki, W., 1965. Genetic influence of the Rs locus on susceptibility to avian tumour viruses. I. Neoplasms induced by RPL-12 and three strains of Rous sarcoma virus. Journal of the National Cancer Institute, 35, 857-863
Crittenden, L.B. and Salter, D.W., 1992. A transgene, alv6, that expresses the envelope of subgroup A avian leukosis virus reduces the rate of congenital transmission of a field strain of avian leukosis virus. Poultry Science, 71, 799-806
Crittenden, L.B., Stone, H.A., Reamer, R.H. and Okazaki, W., 1967. Two loci controlling genetic cellular resistance to avian leukosis sarcoma virus. Journal of Virology, 1, 898-994
Crittenden, L.B., Wendel, E.J. and Motta, J.V., 1973. Interaction of genes controlling resistance to RSV (RAV-O). Virology, 52, 373-384
Crittenden, L.B., Salter, D.W. and Federspiel, M.J., 1989. Segregation of viral phenotype and proviral structure of 23 avian leukosis virus inserts in the germ line of chickens. Theoretical and Applied Genetics, 77, 505-515
Dougherty, R.H., Stewart, J.A. and Morgan, H.R., 1960. Quantitative studies of the relationship between infecting dose of Rous sarcoma virus, antiviral immune response and tumour growth in chickens. Virology, 11, 349-370
Duff, R.G. and Vogt, P.K., 1969. Characteristics of two new avian tumour virus subgroups. Virology, 39, 18-27
Gyles, N.R., Stewart, B.R. and Brown, C.J., 1968. Mechanisms of genetic resistance in the chicken to Rous sarcoma virus. Poultry Science, 47, 430-450
Pani, P.K., 1975. Genetic control of resistance of chick embryo cultures to RSV(RAV-50). Journal of General Virology, 27, 163-172
Pani, P.K. and Ross, L.J.N., 1976. 2-Deoxy-d-glucose uptake by chick embryo cells: a biochemical indicator of genetic susceptibility to RNA tumour viruses. Journal of General Virology, 32, 97-107
Pani, P.K., Kishore, S. and Naithani, S., 1988. Hatchability and mortality following infection of chick embryos with subgroup A Rous sarcoma virus. Avian Pathology, 17, 533-545
Payne, L.N. and Biggs, P.M., 1966. Genetic basis of cellular susceptibility to the Schmidt-Ruppin and Harvis strain of RSV. Virology, 29, 190-198
Payne, L.N. and Biggs, P.M., 1970. Genetic resistance of fowl to MH2 reticuloendothelioma virus. Journal of General Virology, 7, 177-185
Payne, L.N., Holmes, A.E., Howes, K., Pattison, M. and Willems, D.E., 1979. Studies on association between natural infection of hens, cocks and their progeny with lymphoid leukosis virus. Avian Pathology, 8, 411-424
Prince, A.M., 1958. Quantitative studies on Rous sarcoma virus on the chorioallantoic membrane of chick embryo. Journal of the National Cancer Institute, 20, 147-157
Rout, P.K., Pani, P.K. and Naithani, S., 1993. Genetic control of cellular infection by subgroups A and C RNA tumour viruses in guinea-fowl. Veterinary Research Communications, 17, 153-161
Salter, D.W. and Crittenden, L.B., 1989. Artificial insertion of a dominant gene for resistance to avian leukosis virus into the germline of chickens. Theoretical and Applied Genetics, 77, 447-461
Spencer, J.L. and Chamber, J.R., 1992. Endogenous leukosis viral antigen in eggs from meat type chickens on an avian leukosis virus eradication programme. Avian Pathology, 21, 251-259
Vigier, P., 1959. Reliability of titration of Rous sarcoma virus by the count of pocks produced on the egg chorioallantoic membrane. Virology, 8, 41
Wright, E.S. and Bennet, D.D., 1992. Avian retroviral recombinant expressing foreign envelope delays in tumour formation of an ASV-A induced sarcoma. Vaccine, 10, 375-378
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rout, P., Naithani, S. & Pani, P. The Genetic Control of Susceptibility to Subgroup D RNA Tumour Virus Infection in Commercial Breeds of Chickens. Vet Res Commun 22, 425–434 (1998). https://doi.org/10.1023/A:1006157715086
Issue Date:
DOI: https://doi.org/10.1023/A:1006157715086