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Ocular hypotony after laser suture lysis following trabeculectomy with mitomycin C

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Abstract

Background: To report our experience with laser suture lysis (LSL) following trabeculectomy with mitomycin C, its timing, effectiveness and related complications. Methods: We retrospectively examined 38consecutive eyes of 36 patients that underwent LSL following trabeculectomy with mitomycin C. Results: The mean preLSL intraocular pressure (IOP) was 27.0 mm Hg (SD 6.3, range 16–39 mm Hg) and the postLSL IOP (IOP 1 h after the last session of LSL)was 16.0 mm Hg (SD 7.2, range 3–31 mm Hg). Following the LSL in 7 eyes (7 of 38) hypotony (IOP<6 mm Hg, lasting more than 24 h) developed. Two groups were defined. In group I no hypotony was found after LSL and group II went through a period of hypotony. The time interval between surgery and LSL was significantly shorter in group II (mean 5.7, SD 7.5,range 1–19 days), compared to group I (mean 14.7, SD13.0, range 1–44 days) (p=0.041). The mean final IOP(IOP measured at the last visit) was 13.3 mm Hg (SD3.4, range 6–20 mm Hg) and mean follow-up was 6.1months (SD 3.9, range 2.0–15.2 months). No hypotony was found at final examination. PostLSL IOP and final IOP were significantly lower in group II (p=0.002 and p=0.024 respectively). IOP reduction by LSL was significantly greater in group II (p=0.046). Conclusion: LSL is an effective and safe procedure to lower the IOP following trabeculectomy with mitomycin C. Early application of LSL results in lower final IOPs, but has a higher risk of hypotony.

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Authors and Affiliations

  1. Institute of Ophthalmology, University Hospital Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands

    Yavuz Bardak, Marinus H.M. Cuypers, Maurits A.D. Tilanus & {Catharina A. Eggink

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  1. Yavuz Bardak
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  2. Marinus H.M. Cuypers
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  3. Maurits A.D. Tilanus
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  4. {Catharina A. Eggink
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Bardak, Y., Cuypers, M.H., Tilanus, M.A. et al. Ocular hypotony after laser suture lysis following trabeculectomy with mitomycin C. Int Ophthalmol 21, 325–330 (1997). https://doi.org/10.1023/A:1006024522541

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