Abstract
The incidence rate of breast cancer in Japanrose more than two-fold from 1959–60 to 1983–87.To assess to what extent this increase canbe explained by changes in the prevalence offour major risk factors of breast cancer (i.e.age at menarche, age at first birth, ageat menopause, and parity), we estimated the probabilityof developing breast cancer based on the jointdistribution and relative risks of these four riskfactors. The age-specific incidence rate during 1959–60 reportedby the Miyagi Prefectural Cancer Registry was usedto estimate the baseline hazard rate for womenwithout the four risk factors in the sameage group. Assuming that the baseline hazard rateis constant during all periods, we calculated theexpected incidence rates during the periods of 1959–60,1962–64, 1968–71, 1973–77, 1978–81, and 1983–87 for eachage group. Large discrepancies were noted between theobserved and expected incidence rates during 1983–87 inall age groups. The change in the jointdistribution of the four risk factors accounted forless than 40% of the increase observed from1959–60 to 1983–87, suggesting the effects of otherpowerful risk factors.
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Doll R, Payne P, Waterhouse J: Cancer Incidence in Five Continents, volume I. UICC, Berlin, 1966
Parkin DM, Muir C, Whelan SL, Gao Y-T, Ferlay J, Powell J: Cancer Incidence in Five Continents, volume VI. IARC, Lyon, 1992, p 493
Kelsey JL, Gammon MD, John EM: Reproductive factors and breast cancer. Epidemiol Rev 15: 36–47, 1993
Nagata C, Hu Y, Shimizu H: The effects of menstrual and reproductive factors on the risk of breast cancer: meta-analysis of the case-control studies in Japan. Jpn J Cancer Res 86: 910–915, 1995
Statistics and Information Department, Minister's Secretariat, Ministry of Health and Welfare: Vital Statistics of Japan, 1993. Vol 1. Health and Welfare Statistics Association, Tokyo, 1994, pp 80–81, 84–89, 104–105
Hoshi H, Kouchi M: Secular trend of the age at menarche of Japanese girls with special regard to the secular acceleration of the age at peak height velocity. Human Biology 53: 593–598, 1981
Wakai K, Suzuki S, Ohno Y, Kawamura T, Tamakoshi A, Aoki R: Epidemiology of breast cancer in Japan. Int J Epidemiol 24: 285–291, 1995
Minami Y, Takano A, Okuno Y, Fukao A, Kurihara M, Hisamichi S: Trends in incidence of female breast and cervical cancers in Miyagi Prefecture, Japan, 1959–87. Jpn J Cancer Res 87: 10–17, 1996
Wynder EL, Fujita Y, Harris RE, Hirayama T, Hiyama T: Comparative epidemiology of cancer between the United State and Japan. A second look. Cancer 67: 746–763, 1991
Greenland S: Quantitative methods in the review of epidemiologic literature. Epidemiol Rev 9: 1–31, 1987
Doll R, Muir C, Waterhouse J: Cancer Incidence in Five Continents, volume II. UICC, Berlin, 1970, p 205
Waterhouse J, Muir C, Correa P, Powell J: Cancer Incidence in Five Continents, volume III. IARC, Lyon, 1976, p 271
Waterhouse J, Muir C, Shanmugaratnam K, Powell J: Cancer incidence in Five Continents, volume IV. IARC, Lyon, 1982, p 425
Muir C, Waterhouse J, Mack T, Powell J, Whelan S: Cancer Incidence in Five Continents, volume V. IARC, Lyon, 1987, p 455
Mood AM, Graybill FA, Boes DC: Introduction to the Theory of Statistics. McGraw-Hill, New York, 1974, p 181
Mood AM, Graybill FA, Boes DC: Introduction to the Theory of Statistics. McGraw-Hill, New York, 1974, pp 175–198
Institute of Population Problems. Ministry of Health and Welfare. Latest Demographic Statistics. Health and Welfare Statistics Association, Tokyo, 1994, pp 158, 171
Ishizawa M, Anabuki H, Ishikawa S: Studies on the relationship between menarche and malnutrition. Med Biology 23: 99–101, 1952 (in Japanese)
Sasaki N: A survey on factors influencing the menarche. Jpn J Hyg 23: 329–331, 1968 (abstract in English)
Segi M, Fukushima T, Fujisaku S, Kurihara M, Saito S, Asano K, Komori M: An epidemiological study on cancer in Japan. The report of the committee for epidemiological study on cancer, supported by the Ministry of Welfare and Public Health. Gann 48(Suppl): 1–63, 1957
Kato I, Miura S, Kasumi F, Iwase T, Tashiro H, Fujita Y, Koyama H, Ikeda T, Fujiwara K, Saotome K, Asaishi K, Abe R, Nihei M, Ishida T, Yokoe T, Yamamoto H, Murata M: A case-control study of breast cancer among Japanese women: with special reference to family history and reproductive and dietary factors. Breast Cancer Res Treat 24: 51–59, 1992
Wakai K, Ohno Y, Watanabe S, Sakamoto G, Kasumi F, Suzuki S, Kubo-Fujiwara N: Risk factors for breast cancer among Japanese women in Tokyo: A case-control study. J Epidemiol 4: 71–71, 1994
Hu Y-H, Nagata C, Shimizu H, Kaneda N, Kashiki Y: Association of body mass index, physical activity and reproductive histories with breast cancer: a case-control study in Gifu, Japan. Breast Cancer Res Treat 1997 (in press)
Hirohata T, Shigematsu T, Nomura AM, Nomura Y, Horie A: Occurrence of breast cancer in relation to diet and reproductive history: a case-control study in Fukuoka, Japan. Natl Cancer Inst Monogr 69: 187–190, 1985
Howe GR, Friedenreich CM, Jain M, Miler AB: A cohort study of fat intake and risk of breast cancer. J Natl Cancer Inst 83: 336–340, 1991
Willet WC: Prospective studies of diet and breast cancer. Cancer 74: 1085–1089, 1994
Graham S, Hellmann R, Marshall J, Freudenheim J, Vena J, Swanson M, Zielezny M, Memoto T, Stubbe N, Raimondo T: Nutritional epidemiology of postmenopausal breast cancer in Western New York. Am J Epidemiol 134: 552–556, 1991
Van den Brandt PA, van't Veer P, Goldbohm RA, Orant E, Volovics A, Hermus RJ, Sturmans F: A prospective cohort study on dietary fat and the risk of postmenopausal breast cancer. Cancer Res 53: 75–82, 1993
London SJ, Colditz GA, Stampfer MJ, Willet WC, Rosner B, Speizer FE: Prospective study of relative weight, height, and risk of breast cancer. J Am Med Assoc 262: 2853–2858, 1989
Hunter DJ, Willet WC: Diet, body size and breast cancer. Epidemiol Rev 15: 110–132, 1993
Tretli S: Height and weight in relation to breast cancer morbidity and mortality. A prospective study of 570,000 women in Norway. Int J Cancer 44: 23–30, 1989
Health and Welfare Statistics Association: J Health & Welfare Statistics 41: 82–86, 1994
Rosenberg L, Metzger, Palmer R: Alcohol consumption and risk of breast cancer: A review of the epidemiologic evidence. Epidemiol Rev 15: 133–144, 1993
Health and Welfare Statistics Association: J Health & Welfare Statistics 34: 127, 1986
Ministry of Health and Welfare, Japan: Summary of National Survey of Circulatory Disorders, 1990, p 130
Kato I, Tominaga S, Terao C: Alcohol consumption and cancers of hormone-related organs in females. Jpn J Clin Oncol 19: 202–207, 1989
Hirose K, Tajima K, Hamajima N, Inoue M, Takezaki T, Kuroishi T, Yoshida M, Tokudome S: A large-scale, hospital-based case-control study of risk factors of breast cancer according to menopausal status. Jpn J Cancer Res 86: 146–154, 1995
Hirayama T: Epidemiology of breast cancer. Jpn J Cancer Clinics 1: 336–347, 1955 (in Japanese)
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Nagata, C., Kawakami, N. & Shimizu, H. Trends in the incidence rate and risk factors for breast cancer in Japan. Breast Cancer Res Treat 44, 75–82 (1997). https://doi.org/10.1023/A:1005726110649
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DOI: https://doi.org/10.1023/A:1005726110649