Skip to main content
SpringerLink
Log in

Analysis of plasmenylethanolamines using electrospray tandem mass spectrometry and its application in screening for peroxisomal disorders

  • Published:
Journal of Inherited Metabolic Disease

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

REFERENCES

  • Björkhem I, Sisfontes L, Bostrom B, Kase BF, Blomstrand R (1986) Simple diagnosis of the Zellweger syndrome by gas-liquid chromatography of dimethylacetals. J Lipid Res 27: 786–791.

    Google Scholar 

  • Brügger B, Erben G, Sandho. R, Wieland FT, Lehmann WD (1997) Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry. Proc Natl Acad Sci USA 94: 2339–2344.

    Google Scholar 

  • Dacremont G, Vincent G (1995) Assay of plasmalogens and polyunsaturated fatty acids (PUFA) in erythrocytes and fibroblasts. J Inherit Metab Dis 18 (Supplement 1): 84–89.

    Google Scholar 

  • Folch J, Lees M, Sloane-Stanley GH (1957) A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226: 497–509.

    Google Scholar 

  • Han X, Gross RW (1994) Electrospray ionization mass spectroscopic analysis of human erythrocyte plasma membrane phospholipids. Proc Natl Acad Sci USA 91: 10635–10639.

    Google Scholar 

  • Han X, Gubitosi-Klug RA, Collins BJ, Gross RW (1996) Alterations in individual molecular species of human platelet phospholipids during thrombin stimulation: electrospray ionization mass spectrometry-facilitated identification of the boundary conditions for the magnitude and selectivity of thrombin-induced platelet phospholipid hydrolysis. Biochemistry 35: 5822–5832.

    Google Scholar 

  • Kayganich KA, Murphy RC (1992) Fast atom bombardment tandem mass spectrometric identification of diacyl, alkylacyl, and alk-1–enylacyl molecular species of glycerophosphoethanolamine in human polymorphonuclear leukocytes. Anal Chem 64: 2965–2971.

    Google Scholar 

  • Lee TC (1998) Biosynthesis and possible biological functions of plasmalogens. Biochim Biophys Acta 1394: 129–145.

    Google Scholar 

  • van den Bosch H, Schrakamp G, Hardeman D, Zomer AW, Wanders RJ (1993) Ether lipid synthesis and its deficiency in peroxisomal disorders. Biochimie 75: 183–189.

    Google Scholar 

  • Wanders RJ, Schumacher H, Heikoop J, Schutgens RB, Tager JM (1992) Human dihydroxyacetonephosphate acyltransferase deÐciency: a new peroxisomal disorder. J Inherit Metab Dis 15: 389–391.

    Google Scholar 

  • Wanders RJ, Dekker C, Hovarth VA, Schutgens RB, Tager JM, Van Laer PL (1994) Human alkyldihydroxyacetonephosphate synthase deficiency: a new peroxisomal disorder. J Inherit Metab Dis 17: 315–318.

    Google Scholar 

  • Wanders RJ, Tager JM (1998) Lipid metabolism in peroxisomes in relation to human disease. Mol Aspects Med 19: 69–154.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Clinical Chemistry and Emma Children's Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

    P. Vreken, F. Valianpour, H. Overmars, P. G. Barth, J. J. M. Selhorst, A. H. van Gennip & R. J. A. Wanders

Authors
  1. P. Vreken
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. F. Valianpour
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Overmars
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. P. G. Barth
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. J. J. M. Selhorst
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A. H. van Gennip
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. R. J. A. Wanders
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vreken, P., Valianpour, F., Overmars, H. et al. Analysis of plasmenylethanolamines using electrospray tandem mass spectrometry and its application in screening for peroxisomal disorders. J Inherit Metab Dis 23, 429–433 (2000). https://doi.org/10.1023/A:1005676507682

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1005676507682

Keywords

Search

Navigation