Abstract
Mass balances analysis of polyphasic dispersed systems showed that cellular cycling of the substrate involves (a) an increase in the specific metabolisation rate and (b) a decrease in the biomass yield coefficient (energy spilling). In biomass calculations, the substrate release rate can replace the maintenance coefficient concept. Thus, decreasing the substrate transfer rates could improve cells or microorganisms strains of industrial importance.
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Thierie, J. Cellular cycling of substrate as a possible cryptic way for energy spilling in suspended cellular continuous cultures. Biotechnology Letters 22, 1143–1149 (2000). https://doi.org/10.1023/A:1005616520482
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DOI: https://doi.org/10.1023/A:1005616520482