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Docosahexaenoic acid and retinal function in children with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency

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Journal of Inherited Metabolic Disease

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REFERENCES

  • Anderson RE, Benolken RM, Dudley PA, Landis DJ, Wheeler TG (1974) Proceedings: Polyunsaturated fatty acids of photoreceptor membranes. Exp Eye Res 18: 205–213.

    Google Scholar 

  • Birch EE, Birch D, Uauy R (1997) Visual function and essentiality of a-linolenic acid and docosahexaenoic acid in human infants. In Yehuda S, Mostofsky DI, eds. Handbook of Essential Fatty Acid Biology: Biochemistry, Physiology, and Behavioral Neurobiology, Totowa, NJ: Humana Press, 183–199.

    Google Scholar 

  • Gillingham M, Van Calcar S, Ney D, Wolff J, Harding C (1999) Dietary management of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD)-a case report and survey. J Inher Metab Dis 22: 123–131.

    Google Scholar 

  • Infante JP, Huszagh VA (1997) On the molecular etiology of decreased arachidonic (20: 4n—6), docosapentaenoic (22: 5n—6) and docosahexaenoic (22: 6n—3) acids in Zellweger syndrome and other peroxisomal disorders. Mol Cell Biochem 168: 101–115.

    Google Scholar 

  • Moore SA, Hurt E, Yoder E, Sprecher H, Spector AA (1995) Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid. J Lipid Res 36: 2433–2443.

    Google Scholar 

  • Neuringer M, Connor WE, Lin DS, Barstad L, Luck S (1986) Biochemical and functional effects of prenatal and postnatal omega 3 fatty acid deficiency on retina and brain in rhesus monkeys. Proc Natl Acad Sci USA 83: 4021–4025.

    Google Scholar 

  • Sims HF, Brackett JC, Powell CK, et al (1995) The molecular basis of pediatric long chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with maternal acute fatty liver of pregnancy. Proc Natl Acad Sci USA 92: 841–845.

    Google Scholar 

  • Tyni T, Kivela. T, Lappi M, Summanen P, Nikoskelainen E, Pihko H (1998) Ophthalmologic findings in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency caused by the G1528C mutation. Ophthalmology 105: 810–824.

    Google Scholar 

  • Voss A, Reinhart M, Sankarappa S, Sprecher H (1991) The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a Δ4-desaturase. J Biol Chem 266: 19995–20000.

    Google Scholar 

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Authors and Affiliations

  1. The Waisman Center and Department of Pediatrics, University of Wisconsin Medical School, Madison, Wisconsin, USA

    C. O. Harding, M. B. Gillingham, S. C. van Calcar & J. A. Wolff

  2. Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, Wisconsin, USA

    J. N. Verhoeve & M. D. Mills

Authors
  1. C. O. Harding
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  2. M. B. Gillingham
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  3. S. C. van Calcar
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  4. J. A. Wolff
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  5. J. N. Verhoeve
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  6. M. D. Mills
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Harding, C.O., Gillingham, M.B., van Calcar, S.C. et al. Docosahexaenoic acid and retinal function in children with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. J Inherit Metab Dis 22, 276–280 (1999). https://doi.org/10.1023/A:1005502626406

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  • DOI: https://doi.org/10.1023/A:1005502626406

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