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(S)-3-Pentyn-2-ol production through microbial enzyme-catalyzed, highly enantioselective hydrolysis of racemic 3-pentyn-2-ol esters

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Abstract

Air-dried cells of Hansenula nonfermentans AKU 4332 catalyzed the production of (S)-3-pentyn-2-ol from (RS)-3- pentyn-2-ol acetate ester at 10% (v/v). The product was formed at 96.6% e.e. with a molar yield of 45% in 24 h. © Rapid Science Ltd. 1998

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References

  • Burgess, K., and Jennings, L.D. (1991). J. Am. Chem. Soc., 113, 6129–6139.

    Google Scholar 

  • Gluanzer, B. I., Faber, L. and Griengl, H. (1987). Tetrahedron, 43, 5791–5796.

    Google Scholar 

  • Gluanzer, B. I., Faber, K., and Griengl, H. (1988). Enzyme Microb. Technol., 10, 744–749.

    Google Scholar 

  • Gluanzer, B.I., Konigsberger, B., Berger, B., Faber, K., and Griengl, H. (1990). Chem. Phys. Lipids, 54, 43–48.

    Google Scholar 

  • Kamezawa, M., Raku, T., Tachibana, H., Ohtani, T., and Naoshima, Y. (1995). Biosci. Biotech. Biochem., 59, 549–551.

    Google Scholar 

  • Kawashima, M., and Hasegawa, T. (1992). Biotech. Lett., 14, 1135–1136.

    Google Scholar 

  • Midland, M. M. (1989). Chem. Rev., 89, 1553–1561.

    Google Scholar 

  • Mori, K., and Akao, H. (1990). Tetrahedron, 36, 91–96.

    Google Scholar 

  • Ogawa, J., Xie, S.-X., and Shimizu, S. (1998) Appl. Microbiol. Biotechnol. in press.

  • Ohta H., and Tetsukawa, H. (1980). Agric. Biol. Chem., 44, 863–867.

    Google Scholar 

  • Oritani, T., and Yamashita, K. (1980). Agric. Biol. Chem., 44, 2407–2411.

    Google Scholar 

  • Shimizu, M., Kawanami, H., and Fujisawa, T. (1992). Chemistry Letters, 107–110.

Download references

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Authors and Affiliations

  1. Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-Ku Kyoto, Japan

    Sheng-Xue Xie, Jun Ogawa & Sakayu Shimizu

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  1. Sheng-Xue Xie
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  2. Jun Ogawa
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  3. Sakayu Shimizu
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Xie, SX., Ogawa, J. & Shimizu, S. (S)-3-Pentyn-2-ol production through microbial enzyme-catalyzed, highly enantioselective hydrolysis of racemic 3-pentyn-2-ol esters. Biotechnology Letters 20, 935–938 (1998). https://doi.org/10.1023/A:1005497825103

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  • DOI: https://doi.org/10.1023/A:1005497825103

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