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Analysis of the Neuronal Background Impulse Activity in the Rat Locus Coeruleus

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Abstract

Using several techniques of statistical analysis, we studied in detail the extracellularly recorded background impulse activity (BA) of neuronal elements of the rat locus coeruleus (LC). Impulse trains generated by most LC neurons were stationary and demonstrated different levels of regularity; a nonstationary type of BA was observed in 17% of the neurons under study. Statistical parameters of the BA generated by LC neurons showed a wide variability. Distributions of the BA interspike intervals (ISI) of most LC neurons were characterized by more or less expressed bimodality or polymodality. Serial correlation analysis of the ISI durations both in stationary and nonstationary spike trains allowed us to differentiate five main types of the dynamics of ISI successions in the BA of LC neurons.

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Authors and Affiliations

  1. Geratsi Yerevan State Medical University, Republic of Armenia

    D. N. Khudaverdyan, A. A. Asratyan & I. V. Varderesyan

  2. Abovyan Armenian Pedagogical Institute, Yerevan, Republic of Armenia

    M. V. Khanbabyan, R. Sh. Sarkisyan & G. Kh. Mushegyan

Authors
  1. D. N. Khudaverdyan
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  2. A. A. Asratyan
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  3. I. V. Varderesyan
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  4. M. V. Khanbabyan
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  5. R. Sh. Sarkisyan
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  6. G. Kh. Mushegyan
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Khudaverdyan, D.N., Asratyan, A.A., Varderesyan, I.V. et al. Analysis of the Neuronal Background Impulse Activity in the Rat Locus Coeruleus. Neurophysiology 32, 271–275 (2000). https://doi.org/10.1023/A:1005212309694

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