Abstract
The mycocinogenous strain Tilletiopsis flava VKM Y-2823 was found to possess fungicidal activity at pH 3.5–4.5, which was retained after curing the strain by eliminating the extrachromosomal genetic elements. The mycocin produced by the strain had a molecular mass of more than 10 kDa and was readily inactivated by heating and treatment with protease K. This mycocin was found to be active against species of the anamorphic genus Tilletiopsis. The overwhelming majority of other representatives of the order Tilletiales, as well as ascomycetous and basidiomycetous (including ballistosporous) yeasts of the orders Sporidiales and Tremellales, were resistant to it.
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Golubev, V.I., Churkina, L.G. Specificity of Yeast Sensitivity to the Mycocin of Tilletiopsis flava VKM Y-2823. Microbiology 70, 41–44 (2001). https://doi.org/10.1023/A:1004888603762
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DOI: https://doi.org/10.1023/A:1004888603762