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Lactate Dehydrogenase Activity and Insulin and Lactate Levels at an Altitude Below Sea Level (–350 m) Compared to Those at an Altitude Above Sea Level (620 m) After Exercise

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Abstract

This study was designed to investigate the effect of exercise at 350 m below sea level altitude (–350 m) on the serum levels of lactate dehydrogenase (LDH), insulin, and lactate. The study was carried out on ten trained adult males with mean age of 23.3 ± 3.4 years following a 21-km noncompetitive run. Venous blood was withdrawn from the subjects before exercise and 5 min post exercise. For comparison purposes, a similar study was performed with the same subjects but at 620 m above sea level (+620 m). The results show a significant increase in LDH and lactate levels after exercise only at low altitude (–350 m). Serum insulin levels decreased significantly after exercise at both altitudes. These changes in serum levels of LDH, insulin, and lactate at different altitudes suggest that a type of metabolic adjustment is present that meets energy requirements during exercise.

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Authors and Affiliations

  1. Departments of Biochemistry and Physiology, School of Medicine, Jordan University of Science and Technology, P.O. Box 3030, Irbid, Jordan

    F. El-Migdadi, S. Y. Khatib & N. Bashir

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  1. F. El-Migdadi
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  2. S. Y. Khatib
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  3. N. Bashir
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El-Migdadi, F., Khatib, S.Y. & Bashir, N. Lactate Dehydrogenase Activity and Insulin and Lactate Levels at an Altitude Below Sea Level (–350 m) Compared to Those at an Altitude Above Sea Level (620 m) After Exercise. Biochemistry (Moscow) 66, 96–98 (2001). https://doi.org/10.1023/A:1002846032470

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