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Behavior Genetics

, Volume 30, Issue 5, pp 359–366 | Cite as

A Study of the Genetic and Environmental Etiology of Stuttering in a Selected Twin Sample

  • S. Felsenfeld
  • K. M. Kirk
  • G. Zhu
  • D. J. Statham
  • M. C. Neale
  • N. G. Martin
Article

Abstract

Stuttering is a developmental disorder of speech production that usually emerges in childhood. In this study, a large population-based twin sample from the Australian Twin Registry (1567 pairs and 634 singles aged 17–29 years) was screened to identify twin pairs in which one or both members reported themselves to be affected by stuttering. Telephone interview-based diagnoses were obtained for 457 of these individuals (self-reported affected cases, cotwins, and controls) to determine whether the self-report was correct. To correct for ascertainment bias we carried out a bivariate analysis of the final diagnosis in the selected sample with the screening item in the full sample, using the categorical raw data option of Mx 1.47c. After correcting for ascertainment bias, approximately 70% (95% confidence interval: 39–86%) of the variance in liability to stuttering was found to be attributable to additive genetic effects, with the remainder due to nonshared environmental effects.

Twins stuttering speech disorders bivariate analysis ascertainment bias 

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Copyright information

© Plenum Publishing Corporation 2000

Authors and Affiliations

  • S. Felsenfeld
  • K. M. Kirk
  • G. Zhu
  • D. J. Statham
  • M. C. Neale
  • N. G. Martin

There are no affiliations available

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