Abstract
The stereotyped hyperkinesis referred to as pendulum movements (PM) may be found in up to 50% of the animals in stocks of Wistar rats. The mode of inheritance of predisposition to PM was studied by two methods: 1) a classical Mendelian analysis of hybrids of the strains PM+ and PM− bred from Wistar stock for enhancement and absence of PM, respectively, and 2) a segregation analysis of pedigree data from the archive records of breeding the cataleptic GC strain. The two methods gave the same result: the inheritance of predisposition to PM can be explained by a major gene model with an incomplete penetrance of heterozygous genotype.
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Barykina, N.N., Kolpakov, V.G., Alekhina, T.A. et al. Inheritance of Pendulum Movements in Rats. Behav Genet 30, 77–81 (2000). https://doi.org/10.1023/A:1002094728510
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DOI: https://doi.org/10.1023/A:1002094728510