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Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells

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Abstract

Addition of Epithalon peptide in telomerase-negative human fetal fibroblast culture induced expression of the catalytical subunit, enzymatic activity of telomerase, and telomere elongation, which can be due to reactivation of telomerase gene in somatic cells and indicates the possibility of prolonging life span of a cell population and of the whole organism.

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Authors and Affiliations

  1. North-Western Division of Russian Academy of Medical Sciences, St. Petersburg Institute of Bioregulation and Gerontology, Russia

    V. Kh. Khavinson, I. E. Bondarev & A. A. Butyugov

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  1. V. Kh. Khavinson
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  2. I. E. Bondarev
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  3. A. A. Butyugov
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Correspondence to V. Kh. Khavinson.

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Khavinson, V.K., Bondarev, I.E. & Butyugov, A.A. Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells. Bulletin of Experimental Biology and Medicine 135, 590–592 (2003). https://doi.org/10.1023/A:1025493705728

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