Abstract
In the thew frog Rana ridibunda, local microphoretic injections of horseradish peroxidase into various parts of spinal cord were used for study of trajectory of retrograde enzyme-labeled fiber systems and topography of labeled neurons in vestibulospinal nuclei, the source of vestibulospinal fibers. The vestibulospinal tracts were shown to be formed by neurons of lateral vestibular nucleus, although descending vestibular nucleus also is partially involved, while medial vestibular nucleus contributes to even lesser degree. Besides, study of spatial distribution of C- and L-vestibulospinal neurons in the frog did not confirm the presence of the definite somatotopy that is characteristic of vestibular nuclei in mammals.
Similar content being viewed by others
REFERENCES
Kappers, A.C.U., Huber, G.C., and Grosby, E.C., The Comparative Anatomy of the Nervous System of Vertebrates, Including Man, vol. 1, New York: Hafner, 1960.
Maeda, M., Magherini, P.C., and Precht, W., Functional Organization of Vestibular and Visual Inputs to Neck and Forelimb Motoneurons in the Frog, J. Neurophysiol., 1977, vol. 40, pp. 225-243.
Magherini, P.C., Precht, W., and Richter, A., Vestibulospinal Effects of Hindlimb Motoneurons of the Frog, Pflugers Arch., 1974, vol. 348, pp. 211-223.
D'Ascanio, P. and Corvaja, N., Spinal Projections from the Rhombencephalon in the Toad, Arch. Ital. Biol., 1981, vol. 119, pp. 139-150.
Fuller, P.M., Projections of the Vestibular Nuclear Complex in the Bullfrog (Rana catesbeiana), Brain Behav. Evol., 1974, vol. 10, pp. 157-169.
Toth, P., Csank, G., and Lazar, G., Morphology of the Cells of Origin of Descending Pathways to the Spinal Cord in Rana esculenta. A Tracing Study Using Cobaltic-Lysine Complex, J. Hirnforsch., 1985, vol. 26, pp. 365-383
Ten Donkelaar, H.J., The Central Nervous System of Vertebrates, vol. 2, New York: Springer, 1997, pp. 1151-1314.
Corvaja, N. and Grofova, I., Vestibulospinal Projections in the Toad. An Experimental Electron Microscopic Study, Neurosci., 1978, vol. 3, pp. 619-628.
Corvaja, N. and Grofova, I., Vestibulospinal Projections in the Toad, Basic Aspects of Central Vestibular Mechanisms, Brodal, A. and Pompeiano, O., Eds., Progress in Brain Research,Amsterdam: Elsevier, 1972, vol. 37, pp. 297-307.
Ten-Donkelaar, H.J., De Boer-Van Huizen, R., Schouten, F.T.M., and Eggen, S.J.H., Cells of Origin of Descending Pathways to the Spinal Cord in the Clawed Toad (Xenopus laevis), Neurosci., 1981, vol. 6, pp. 2297-2312.
Matesz, C., Central Projection of the VIIIth Cranial Nerve in the Frog, Neurosci., 1979, vol. 4, pp. 2061-2071.
Cruce, W.L.R., A Supraspinal Monosynaptic Input to Hindlimb Motoneurons in Lumbar Spinal Cord of the Frog, Rana catesbeiana, J. Neurophysiol., 1974, vol. 37, pp. 691-704.
Shapovalov, A.I., Neuronal Organization and Synaptic Mechanisms of Supraspinal Motor Control in Vertebrates, Rev. Physiol. Biochem. Pharmacol., 1975, vol. 72, pp. 1-54.
Shapovalov, A.I., Neirony i sinapsy supraspinal.nykh motornykh sistem (Neurons and Synapses of Supraspinal Motor Systems), Leningrad, 1975.
Chmykhova, N.M. and Babalyan, A.L., Structural and Functional Characteristics of Supraspinal Fibers Connected Monosynaptically with Lumbar Motoneurons of the Spinal Cord of the Frog Rana ridibunda, Zh. Evol. Biokhim. Fiziol., 1998, vol. 34, 458-470.
Mesulam, M.-M., Tetramethyl Benzydine for HRP Neurochemistry: A Noncarcinogenic Blue Reaction-Product with Superior Sensitivity for Visualizing Neural Afferents and Efferents, J. Histochem. Cytochem., 1978, vol. 26, pp. 106-117.
Kemali, M. and Braitenberg, V., Atlas of the Frog.s Brain, Berlin: Springer, 1969.
Kuruvilla, A., Sitko, S., Schwartz, I.R., and Honrubia, V., The Central Projections of Primary Vestibular Fibers in the Bullfrog: 1. The Vestibular Nuclei, Laryngoscope, 1985, vol. 95, pp. 692-707.
Fanardjian, V.V., Manvelyan, L.R., and Nasoyan, A.M., Spatial Distribution of the Vestibulospinal Neurons in the Frog Vestibular Nuclei, Neurosci., 2001, vol. 104, pp. 853-862.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Pogosyan, V.I., Arutyunyan, T.L., Aglintsyan, T.S. et al. Morphological Study of Spatial Distribution of Vestibulospinal Neurons in the Frog Rana ridibunda . Journal of Evolutionary Biochemistry and Physiology 38, 773–780 (2002). https://doi.org/10.1023/A:1022886110902
Issue Date:
DOI: https://doi.org/10.1023/A:1022886110902