In Vitro Fertilization Treatment in Genital Tuberculosis

  • I. Soussis
  • G. Trew
  • I. Matalliotakis
  • R. Margara
  • R. M. L. Winston


Purpose: We describe our experience with in vitro fertilization (IVF) treatment in 13 women with histologically proven genital tuberculosis.

Methods: For IVF treatment the above patients had to meet two criteria: normal uterine cavity and functional ovaries.

Results: Six intrauterine pregnancies (28.6% success rate) were achieved after 21 IVF treatment cycles in 13 patients with histologically proven diagnoses of genital tuberculosis. This series represents a comparatively encouraging success rate, but these patients were selected carefully before committing them to IVF treatment.

Conclusions: IVF represents a useful treatment and improves the chances of fertility, in what was considered a desperate situation.

tuberculosis infertility in vitro fertilization 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Schaefer G: Female genital tuberculosis. Clin Obstet Gynecol 1976;19:223–234Google Scholar
  2. 2.
    Marcus SF, Rizk B, Fountain S, et al.: Tuberculous infertility and in vitro fertilization. Am J Obstet Gynecol 1994;171:1593–1596Google Scholar
  3. 3.
    Falk V, Ludvikson K, Agren G: Genital tuberculosis in women. Analysis of 187 newly diagnosed cases from 47 Swedish hospitals during the ten year period 1968 to 1977. Am J Obstet Gynecol 1980;138:974–977Google Scholar
  4. 4.
    Gurgan T, Urman B, Yarali H: Results of in vitro fertilization and embryo transfer in women with infertility due to genital tuberculosis. Fertil Steril 1996;65:367–370Google Scholar
  5. 5.
    Frydman R, Eibschitz I, Belaisch-Allart JC, et al.: In vitro fertilization in tuberculous infertility. J In Vitro Fert Embryo Transfer 1985;4:184–189Google Scholar
  6. 6.
    Klein TA, Richmond JA, Mishell DR Jr: Pelvic tuberculosis. Obstet Gynecol 1976;48:99–104Google Scholar
  7. 7.
    Le Coutour X, Delecour M, Leroy JL, et al.: Does genital tuberculosis still exist? Recent review. J Gynecol Obstet Biol Reprod 1984;13:419–423Google Scholar
  8. 8.
    Telenti A, Imboden P, Marchesi F, et al.: Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis. Lancet 1993;13:341(8846):647–650Google Scholar
  9. 9.
    Gupta S: Pelvic tuberculosis in women. J Obstet Gynaecol India 1957;7:181Google Scholar
  10. 10.
    Chattopadyay SK, Sengupta BS, Edrees YB, et al.: The pattern of female genital tuberculosis in Riyadh, Saudi Arabia. Br J Obstet Gynaecol 1986; 93:367–371Google Scholar
  11. 11.
    Adrai J, Blanc B, Ruf H, et al.: La sterilite de la femme nordafricaine immigree. Rev Fr Gynecol Obstet 1985;80(10):733–736Google Scholar
  12. 12.
    De-Vynck WE, Kruger TF, Joubert JJ, et al.: Genital tuberculosis associated with female infertility in the Western Cape. S Afr Med J 1990;77(12):630–631Google Scholar
  13. 13.
    Oosthuizen, AP, Wessels PH, Hefer JN: Tuberculosis of the female genital tract in patients attending an infertility clinic. S Afr Med J 1990;77(11):562–564Google Scholar
  14. 14.
    Tumarov IP, Kochorova MN: Use of microsurgical technics in the treatment of tubal infertility of tuberculous etiology. Probl Tuberk 1990;2:6–8Google Scholar
  15. 15.
    Winston RML, Margara RA: Microsurgical salpingostomy is not an obsolete procedure. Br J Obstetrics Gynaecol 1991;673–642Google Scholar

Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • I. Soussis
    • 1
  • G. Trew
    • 1
  • I. Matalliotakis
    • 1
  • R. Margara
    • 1
  • R. M. L. Winston
    • 1
  1. 1.Institute of Obstetrics and Gynaecology, Royal Postgraduate Medical SchoolHammersmith HospitalLondonUK

Personalised recommendations