Skip to main content
Log in

Head and neck cancer

  • Published:
Cancer and Metastasis Reviews Aims and scope Submit manuscript

Abstract

In this review, the authors outline the epidemiology, genetic factors, treatment and outcomes of head and neck cancer.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Poole ME, Sailer SL, Rosenman JG, Tepper JE, Weissler MC, Shockley WW, Yarbrough WG, Pillsbury HC III, Schell MJ, Bernard SA: Chemoradiation for locally advanced squamous cell carcinoma of the head and neck for organ preservation and palliation. Arch Oto HNS 127(12): 1446-1450, 2001

    Google Scholar 

  2. Papadimitrakopoulou VA: Carcinogenesis of head and neck cancer and the role of chemoprevention in its reversal. Curr Opin Onc 12(3): 240-245, 2000

    Google Scholar 

  3. Hoffman HT, Karnell LH, Funk GF, Robinson RA, Menck HR: The National Cancer Data Base report on cancer of the head and neck. Arch Oto HNS 124(9): 951-962, 1998

    Google Scholar 

  4. Funk GF, Karnell LH, Robinson RA, Zhen WK, Trask DK, Hoffman HT: Presentation, treatment, and outcome of oral cavity cancer: A national cancer data base report. Head Neck 24(2): 165-180, 2002

    Google Scholar 

  5. Levine PA, Seidman D: Neoplasms of the oral cavity. In: Bailey BJ (ed) Head and Neck Surgery-Otolaryngology. Lippincott-Raven Publishers, Philadelphia, PA, 1998, pp 1523-1539

    Google Scholar 

  6. Seikaly H, Rassekh CH: Oropharyngeal cancer. In: Bailey BJ, (ed) Head and Neck Surgery-Otolaryngology. Lippincott-Raven Publishers, Philadelphia, PA, 1998, pp 1655-1671

    Google Scholar 

  7. Schechter GL, Wadsworth TT: Hypopharyngeal cancer. In: Bailey BJ (ed) Head and Neck Surgery-Otolaryngology. Lippincott-Raven Publishers, Philadelphia, PA, 1998, pp 1673-1691

    Google Scholar 

  8. Fried MP, Gopal HV, Frankenthaler R: Advanced cancer of the larynx. In: Bailey BJ (ed) Head and Neck Surgery-Otolaryngology. Lippincott-Raven Publishers, Philadelphia, PA, 1998, pp 1739-1758

    Google Scholar 

  9. Collins SL: Squamous cell carcinoma of the oral cavity, oropharynx, pharyngeal wall, and nasopharynx. In: Ballenger JJ, Snow JB (eds) Otorhinolaryngology-Head and Neck Surgery. Williams & Wilkins, Media, PA, 1996, pp 249-368

    Google Scholar 

  10. Ahmed KA, Robbins KT, Wong F, Salazar JE: Efficacy of concomitant chemoradiation and surgical salvage for N3 nodal disease associated with upper aerodigestive tract carcinoma. Laryngoscope 110(11): 1789-1793, 2000

    Google Scholar 

  11. Lazarus P, Park JY: Metabolizing enzyme genotype and risk for upper aerodigestive tract cancer. Oral Onc 36(5): 421-431, 2000

    Google Scholar 

  12. Lyon JL, Gardner K, Gress RE: Cancer incidence among Mormons and non-Mormons in Utah 1971-85. Can Causes & Control 5(2): 149-156, 1994

    Google Scholar 

  13. Gritz ER, SchachererC, Koehly L, Nielsen IR, Abemayor E: Smoking withdrawal and relapse in head and neck cancer patients. Head & Neck 21(5): 420-427, 1999

    Google Scholar 

  14. Hong WK, Endicott J, Itri L, Doos W, Batsakis JG, Bell R, Fofonoff S, Byers R, Atkinson EN, Vaughan C: 13-Cis retinoic acid in the treatment of oral leukoplakia. N Engl J Med 315: 1501-1505, 1986

    Google Scholar 

  15. Schantz SP, Huang Q, Shah K, Murty VV, Hsu TC, Yu G, Andersen PE, Huvos AG, Chaganti RS: Mutagen sensitivity and environmental exposures as contributing causes of chromosome 3p losses in head and neck cancers. Carcinogenesis 21(6): 1239-1246, 2000

    Google Scholar 

  16. Salesiotis AN, Cullen KJ: Molecular markers predictive of response and prognosis in the patient with advanced squamous cell carcinoma of the head and neck: Evolution of a model beyond TNM staging. Curr Opin Oncol 12(3): 229-239, 2000

    Google Scholar 

  17. Anonymous: Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. The Department of Veterans Affairs Laryngeal Cancer Study Group. New Eng J Med 324(24): 1685-1690, 1991

    Google Scholar 

  18. Chao KS, Low DA, Perez CA, Purdy JA: Intensity modulated radiation therapy in head and neck cancers: The Mallinckrodt experience. Int J Cancer 90(2): 92-103, 2000

    Google Scholar 

  19. Hu KS, Harrison, LB: Altered fractionation in the treatment of head and neck cancer. Curr Oncol Reports 1(2): 110-123, 1999

    Google Scholar 

  20. Schechter NR, Gillenwater AM, Byers RM, Garden AS, Morrison WH, Nguyen LN, Podoloff DA, Ang KK: Can positron emission tomography improve the quality of care for head-and-neck cancer patients? Int J Rad Onc Bio Phy 51(1): 4-9, 2001

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Amy Y. Chen.

Rights and permissions

Reprints and permissions

About this article

Cite this article

McMahon, S., Chen, A.Y. Head and neck cancer. Cancer Metastasis Rev 22, 21–24 (2003). https://doi.org/10.1023/A:1022203816340

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1022203816340

Navigation