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Electrodiffusion Model Simulation of Rectangular Current Pulses in a Biological Channel

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Abstract

Numerical simulations are presented of stochastic-in-time current pulses for an electrodiffusion model of the biological channel, with a fixed applied voltage across the channel. The electrodiffusion model consists of the advection-diffusion equation coupled either to Gauss' law or Poisson's equation, depending on the choice of boundary conditions, plus a model for the protein charge density in thechannel.

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Authors and Affiliations

  1. Department of Mathematics, Arizona State University, Tempe, AZ, 85287-1804, USA

    Carl L. Gardner

  2. Department of Mathematics, Northwestern University, Evanston, IL, 60208, USA

    Joseph W. Jerome

  3. Department of Molecular Biophysics and Physiology, Rush Medical College, Chicago, IL, 60612, USA

    Robert S. Eisenberg

Authors
  1. Carl L. Gardner
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  2. Joseph W. Jerome
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  3. Robert S. Eisenberg
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Gardner, C.L., Jerome, J.W. & Eisenberg, R.S. Electrodiffusion Model Simulation of Rectangular Current Pulses in a Biological Channel. Journal of Computational Electronics 1, 347–351 (2002). https://doi.org/10.1023/A:1020743423143

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  • DOI: https://doi.org/10.1023/A:1020743423143

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