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Mimicking Gangliosides by Design: Mimics of GM1 Headgroup

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Abstract

Detailed knowledge of the three-dimensional structure of ganglioside headgroups has allowed the successful design of structural and functional mimics of ganglioside GM1 oligosaccharide. Our recent work in this area is reviewed in this paper.

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Authors and Affiliations

  1. Dipartimento di Chimica Organica e Industriale, Universita' di Milano, via Venezian 21, 20133, Milano, Italy

    Anna Bernardi & Daniela Arosio

  2. Dipartimento di Chimica e Biochimica Medica, LITA di Segrate, Universita' di Milano, via Fratelli Cervi 93, Segrate Milano, Italy

    Sandro Sonnino

Authors
  1. Anna Bernardi
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  2. Daniela Arosio
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  3. Sandro Sonnino
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Bernardi, A., Arosio, D. & Sonnino, S. Mimicking Gangliosides by Design: Mimics of GM1 Headgroup. Neurochem Res 27, 539–545 (2002). https://doi.org/10.1023/A:1020251428217

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