Abstract
High selectivity has been discovered for the C-alkylation of ambident anions of 5-oxo-1H-4,5-dihydroindeno[1,2-b]pyridines with ethyl bromoacetate, allyl, propargyl, and phenacyl bromides, which leads to the formation of the corresponding 4a-substituted 5-oxo-4H-4a,5-dihydroindeno[1,2-b]pyridines in high yield.
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Muceniece, D., Stupnikova, S. & Lusis, V. 4a-Alkyl Derivatives of 5-Oxo-4H-4a,5-dihydroindeno[1,2-b]pyridine. Chemistry of Heterocyclic Compounds 37, 981–986 (2001). https://doi.org/10.1023/A:1012787517710
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DOI: https://doi.org/10.1023/A:1012787517710