The incidence and reporting of adverse drug reactions in the Division of Psychiatry

Abstract

Objective: to determine the incidence, severity and reporting of adverse drug reactions occurring to newly marketed drug (all drugs annotated with a black triangle symbol) in the Division of Psychiatry.

Method: all patient commenced on a black triangle drug in the previous month and satisfying all inclusion criteria were interviewed by a pre‐registration pharmacist. The investigator collected details regarding drug prescribed, side effects reported and non‐compliance. Reports sent to the CSM were noted.

Results: Twenty‐two patients received 25 black triangle drugs. Sixteen (60%) suffered an adverse drug reaction. Eight reported these to their doctor with 7 (28%) discontinuing treatment due to the severity of the side effects. Two adverse drugs reactions were classified as serious according to CSM criteria (jerking movements, rash), 3 further reactions led to a deterioration in the patients mental state. No yellow cards were completed.

Conclusion: both patient and health care professionals underreport adverse drug reactions. All reactions to a black triangle drug should be reported. A medicines and healthy living group attended by patients and professionals involved in their case has allowed an increased awareness, monitoring and reporting of adverse drug reactions.