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Journal of Fluorescence

, Volume 11, Issue 3, pp 177–185 | Cite as

Ultrasensitive Microscopy of the Plasma Membrane of Living Cells

  • G. J. Schütz
  • M. Sonnleitner
  • H. Schindler
Article

Abstract

The view of the plasma membrane of biological cells was dramatically changed due to the discovery of lipid domains. Initially found as structurally distinct areas characterized by a specific protein content, the concept of lipid domains was rapidly taken over as a new scheme for explaining membrane targeted cellular processes. In this review, we discuss the capabilities of imaging methodologies to study lipid domains and their contributions to the current model of the cellular plasma membrane.

Lipid microdomains cell membrane single molecule microscopy fluorescence microscopy 

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Copyright information

© Plenum Publishing Corporation 2001

Authors and Affiliations

  • G. J. Schütz
    • 1
  • M. Sonnleitner
    • 1
  • H. Schindler
    • 1
  1. 1.Institute for BiophysicsUniversity of LinzLinzAustria

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