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Nocodazole Treatment of CV-1 Cells Enhances Nuclear/Perinuclear Accumulation of Lipid-DNA Complexes and Increases Gene Expression

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REFERENCES

  1. S. Li and L. Huang. Nonviral gene therapy: promises and challenges. Gene Ther. 7:31-34 (2000).

    Google Scholar 

  2. X. Gao and L. Huang. Cationic liposome-mediated gene transfer. Gene Ther. 2:710-722 (1995).

    Google Scholar 

  3. S. F. Hamm-Alvarez and M. P. Sheetz. Microtubule-dependent vesicle transport: Modulation of channel and transporter activity in liver and kidney. Physiol. Rev. 78:1109-1129 (1998).

    Google Scholar 

  4. S. F. Hamm-Alvarez. Targeting endocytosis and motor proteins to enhance DNA persistence. Pharm. Sci. Tech. 2:190-196 (1999).

    Google Scholar 

  5. S. F. Hamm-Alvarez, M. Sonee, K. Loran-Goss, and W-C. Shen. Paclitaxel and nocodazole differentially alter endocytosis in cultured cells. Pharm. Res. 13:1647-1655 (1996).

    Google Scholar 

  6. N. R. Chowdhury, R. M. Hays, V. R. Bommineni, N. Franki, J. R. Chowdhury, C. H. Wu, and G. Y. Wu. Microtubular disruption prolongs the expression of human bilirubin-uridinephosphoglucuronate-glucuronosyltransferase-1 gene transferred into Gunn rat livers. J. Biol. Chem. 271:2341-2346 (1996).

    Google Scholar 

  7. S. Haldar, J. Chintapalli, and C. M. Croce. Taxol induces bcl-2 phosphorylation and death of prostate cancer cells. Cancer Res. 56:1253-1255 (1996).

    Google Scholar 

  8. S. F. Amato, J. M. Swart, M. Berg, H. J. Wanebo, S. R. Mehta, and T. C. Chiles. Transient stimulation of the c-Jun-NH2-terminal kinase/activator protein 1 pathway and inhibition of extracellular signal-regulated kinase are early effects in paclitaxel-mediated apoptosis in human B lymphoblasts. Cancer Res. 58:241-247 (1998).

    Google Scholar 

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Author notes

  1. J. Dezz Ropp

    Present address: InGenuity Systems, Inc., 2160 Gold Street, 2nd Floor, Alviso, California, 95002

Authors and Affiliations

  1. Department of Pharmaceutical Sciences, University of Southern California, Los Angeles, California

    Jimmy Lindberg

  2. Valentis Corporation, Burlingame, California

    Mary Ann M. Fernandez

  3. Valentis Corporation, Burlingame, California

    J. Dezz Ropp

  4. Department of Pharmaceutical Sciences, University of Southern California, Los Angeles, California

    Sarah F. Hamm-Alvarez

Authors
  1. Jimmy Lindberg
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  2. Mary Ann M. Fernandez
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  3. J. Dezz Ropp
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  4. Sarah F. Hamm-Alvarez
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Lindberg, J., Fernandez, M.A.M., Ropp, J.D. et al. Nocodazole Treatment of CV-1 Cells Enhances Nuclear/Perinuclear Accumulation of Lipid-DNA Complexes and Increases Gene Expression. Pharm Res 18, 246–249 (2001). https://doi.org/10.1023/A:1011001022570

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  • DOI: https://doi.org/10.1023/A:1011001022570

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