Abstract
Outdoor acute aquatic toxicity studies with pyridaben and bluegill sunfish (Lepomis macrochirus) and mysid (Mysidopsis bahia) showed that the 96-h LC50s in site-specific water were significantly greater than in classical laboratory studies. In addition, outdoor acute studies showed that pyridaben degrades rapidly in water, in hours, which supports other laboratory and field studies on the fate of pyridaben in aquatic systems. Chronic toxicity to aquatic organisms is not an issue after application in the field because exposures will be brief. The water-effect ratio (WER) of site-specific to laboratory-water 96-h LC50s for L. macrochirus and M. bahia were 18.5 and 24.5, respectively. The lowest WER was used as an application factor with the laboratory LC50 values of several other aquatic organisms to develop “adjusted” site-specific LC50 values. Comparison of the distribution of “adjusted” LC50 values with a distribution of potential environmental exposure concentrations for pyridaben in water indicates minimal acute risk to aquatic organisms. When only acute laboratory data are available, the WER approach is a relevant and realistic means for determining an application factor and for estimating the aquatic hazard/risk assessment of non-persistent pesticides, because it considers a host of factors that affect bioavailability and subsequent toxicity.
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Rand, G.M., Clark, J.R. Hazard/Risk Assessment of Pyridaben: II. Outdoor Aquatic Toxicity Studies and the Water-Effect Ratio. Ecotoxicology 9, 169–177 (2000). https://doi.org/10.1023/A:1008986519187
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DOI: https://doi.org/10.1023/A:1008986519187