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Biochemical biomarkers and potentiation of toxicity

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References

  1. Bell RG. Metabolism of Vit. K and prothrombin synthesis: anticoagulants and Vit. K epoxide cycle. Fed Proc 1978; 37: 2599–604.

    Google Scholar 

  2. Blanchard RA, Furie BC, Furie B. Antibodies specific for bovine abnormal prothrombin. J Biol Chem 1979; 254: 12513–26.

    Google Scholar 

  3. Boon JP, Eijgenraam F, Everaarts JM and Duinker JC. A structure-activity relationship approach towards metabolism of PCBs in marine animals from different trophic levels. Mar Environ Res 1989; 27: 159–76.

    Google Scholar 

  4. Brouwer A. Role of biotransformation in PCB-induced alterations in Vitamin K and thyroid hormone metabolism in laboratory and field species. Biochem Soc Trans 1991; 19: 731–7.

    Google Scholar 

  5. Brouwer A, Van den Berg KJ and Kukler A. Time and dose responses of the reduction in retinoid concentrations in C57/B < R. J. and DBA/2 mice induced by 3,4,3 0,4 0-tetrachlorobiphenyl. Toxicol Appl Pharmacol 1985; 78: 180–9.

    Google Scholar 

  6. Brouwer A, Reijnders PJH and Koeman JH. Polychlorinated biphenyl (PCB)-contaminated fish induces Vitamin K and thyroid hormone deficiency in the common seal (Phoco vitulina). Aquat Toxicol 1989; 15: 99–106.

    Google Scholar 

  7. Brouwer AE, Klasson-Wehler E, Bokdam M, Morse DC and Traag WA. Competitive inhibition of thyroxin binding to transthyretin by monohydroxy metabolites of 3,4,3 0,4 0 tetra-chlorobiphenyl. Chemosphere, 1990; 20: 1257–62.

    Google Scholar 

  8. Castellani S, Mattei A, Renzoni A, Walker CH and Savva D. Preliminary studies on the Use of PCR and DNA fingerprints to detect the Genotoxic Effects of Environmental Chemicals. lst SETAC World Congr Abstr 1993; 246 p.

  9. Cox PR and Smith RH. Rodenticide ecotoxicology: assessing non-target population effects. Funct Ecol 1990; 4: 315–20.

    Google Scholar 

  10. Denison MS, Vella IM and Okey AB. Ah receptor for 2,3,7,8-tetrachloro-dibenzo-p-dioxin in rat liver: lack of sensitivity to alkaline phosphatase when compared to that of glucorticoid receptor. Arch Biochem Biophys 1989; 273: 458–65.

    Google Scholar 

  11. Depledge MH (ed.). The rational basis for detection of the early effect of marine pollutants using physiological indicators. Ambio, 1989; 18: 301–2.

    Google Scholar 

  12. Fergusson D and Walker CH. The inhibition of hepatic cytochrome P450 activities in Japanese quail by anticoagulant rodenticides. 1998; (submitted to Pestic Biochem Physiol).

  13. Fossi MC and Leonzio C (eds.). Proc Int Workshop on Non-destructive Biomarkers in Vertebrates. Lewis Publishers, 1993. Boca Raton, FL, USA.

  14. Gupta RC and Randerath K. Analysis of DNA adducts by 32 P labelling and thin-layer chromatography. In: E Friedberg and PH Hanawalt (Eds.). DNA Repair. 1988; Vol 3. Marcel Dekker, New York. pp. 399–418.

    Google Scholar 

  15. Jackson JB, Thompson HM and Walker CH. The affinity purification of serum carboxylesterase from pigeons. Pestic Sci 1992; 36: 75–8.

    Google Scholar 

  16. Jackson JB, Walker CH, Woods R and Thompson HM. The Development of a Sensitive Assay to Detect the Sublethal Exposure of Pigeons (Columba livia) to Organophosphorus Pesticides. Ist SETAC World Congr. Abstr. 1993; p. 247.

  17. Khattab AD, Walker CH, Mackness MI, Saphier PW. Purification and immunochemical characterisation of pigeon serum butyrylcholinesterase. Implication for environmental monitoring and toxicity testing of birds. Biochem Pharmacol 1993; 4: 991–8.

    Google Scholar 

  18. Khattab AD, Walker CH, Johnston GO and Saphier PW. Identification of butyrylcholinesterase in serum from avian species; methodological aspects and toxicological interpretations. Environmental Toxicology and Chemistry. 1994; 13, 1661–8.

    Google Scholar 

  19. Johnston GD, Collett G, Walker CH, Dawson A, Boyd I, Osborn E. Enhancement of malathion toxicity to the hybrid red-legged paraidge following exposure to prochloraz. Pesticide Biochemistry and Physiology 1989; 35, 107–18.

    Google Scholar 

  20. Johnston GO, Walker CH, Dawson A. Interactive effects between EBI-fungicides (prochloraz, propiconazole and penconazole) and Op insectides (dimethoate, chlorpyriphos, di-azinon and malathion) in the hybrid red-legged partridge. Environ Toxic and Chem 1994a; 13 (4), 615–20.

    Google Scholar 

  21. Johnston G, Walker CH, Dawson A. Potentiation of carbaryl toxicity to the hybrid red-legged partridge following exposure to malathion. Pestic Biochem Physiol 1994b; 49, 198–208.

    Google Scholar 

  22. McCarthy JF, Shugart LR. Biomarkers of Environmental Contamination.1990; Lewis Publishers, Boca Raton FL.

    Google Scholar 

  23. Mineau P (ed.). Cholinesterase-inhibiting Insecticides. Elsevier, 1991; pp. 109–28 Amsterdam, The Netherlands.

  24. Peakall DB. Animal Biomarkers as Pollution Indicators. 1992; Chapman and Hall., London, UK.

    Google Scholar 

  25. Poirier MC. The use of carcinogen-DNA adduct antisera for quantitation and localisation of genomic damage in animal models and human population. Environ Mutagen 1984; 6: 879–87.

    Google Scholar 

  26. Thompson HM and Walker CH. Serum ‘B’ esterases as indicators of exposure to pesticides. In: Proc Int Workshop on Non-destructive Biomarkers in Vertebrates. Lewis publishers, 1993; pp. 35–60. Boca Raton, FL, USA.

  27. Thompson HM, Walker CH, Hardy AR. Avian esterases as indicators of exposure to insecticides-the factor of diurnal variaon. Bull Environ Contam Toxicol 1988a; 41: 4–11.

    Google Scholar 

  28. Thompson HM, Walker CH and Hardy AR. Esterases as indicators of avian exposure to insecticides. In: MP Greaves, BD Smith, PW Greig-Smith (eds.), Environmental Effects of Pescides. BCPC Monograph No. 40, British Crop Protection Council, 1988b; pp. 39–45.

  29. Varanasi V, Reichert WL and Stein JE. 32 P-postlabelling analysis of DNA adducts in liver of wild English sole (Parophys retulis) and winter flounder (Pseudopleuronectes americanus). Cancer Res 1989; 49 (1989) 1171–7.

    Google Scholar 

  30. Varanasi V, Stein JE, Reichert WL, Tilbury KC and Chan SL. Chlorinated and aromatic hydrocarbons in bottom sediments, fish and marine mammals in USA coastal waters: laboratory and field studies of metabolism and accumulation. In: CH Walker, DL Livingstone (eds.). Persistent Pollutants in Marine Ecosystems. Pergamon Press, 1992; pp. 85–118. Oxford, UK.

  31. Walker CH. Biochemical responses as indicators of toxic effects in ecosystems. Toxicol. Lett. 1992; 64/65: 527–33.

    Google Scholar 

  32. Walker CH. Biomarkers and Environmental Risk Assessment. Pesticide Outlook 1996; 7, 7–11.

    Google Scholar 

  33. Walker CH, Hopkin SP, Sibly RM and Peakall D R. Principles of Ecotoxicology, Taylor and Francis, 1996.

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Walker, C. Biochemical biomarkers and potentiation of toxicity. Biotherapy 11, 113–117 (1998). https://doi.org/10.1023/A:1007959210404

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