Origins of life and evolution of the biosphere

, Volume 29, Issue 5, pp 451–461

Silica, Alumina and Clay Catalyzed Peptide Bond Formation: Enhanced Efficiency of Alumina Catalyst

  • Juraj Bujdák
  • Bernd M. Rode
Article

DOI: 10.1023/A:1006524703513

Cite this article as:
Bujdák, J. & Rode, B.M. Orig Life Evol Biosph (1999) 29: 451. doi:10.1023/A:1006524703513

Abstract

Catalytic efficiencies of clay (hectorite), silica and alumina were tested in peptide bond formation reactions of glycine (Gly), alanine (Ala), proline (Pro), valine (Val) and leucine (Leu). The reactions were performed as drying/wetting (hectorite) and temperature fluctuation (silica and alumina) experiments at 85 °C. The reactivity of amino acids decreased in order Gly > Ala > Pro ≈ Val ≈ Leu. The highest catalytic efficiency was observed for alumina, the only catalyst producing oligopeptides in all investigated reaction systems. The peptide bond formation on alumina is probably catalyzed by the same sites and via similar reaction mechanisms as some alumina-catalyzed dehydration reactions used in industrial chemistry.

Copyright information

© Kluwer Academic Publishers 1999

Authors and Affiliations

  • Juraj Bujdák
    • 1
  • Bernd M. Rode
    • 2
  1. 1.Institute of Inorganic ChemistrySlovak Academy of SciencesBratislavaSlovakia
  2. 2.Institute of General, Inorganic and Theoretical ChemistryUniversity of InnsbruckInnsbruckAustria

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