Journal of Autism and Developmental Disorders

, Volume 31, Issue 1, pp 19–28 | Cite as

Autistic Disorder and Schizophrenia: Diagnostic Overlaps

  • M. Mary Konstantareas
  • Terri Hewitt
Article

Abstract

Data on 14 males with autism and 14 with schizophrenia were collected to examine symptom overlap. The Structured Clinical Interview (SCID), the schedule for positive symptoms (SAPS) and the schedule for negative symptoms (SANS) of schizophrenia, the Childhood Autism Rating Scale (CARS), and the DSM-III-R were administered. On the SCID, none of the men with paranoid schizophrenia met criteria for autism while 7 of those with autism met criteria for schizophrenia, disorganized type, showing negative symptoms. In addition, 5 showed positive symptoms on the SAPS and 6 negative symptoms on the SANS. As the difference in measured nonverbal intelligence was not significant, the effects could not be attributed to it. Although the findings continue to support the differentiation of autism and schizophrenia, they are also consistent with a comorbidity of the two disorders, mainly in those diagnosed with autism.

Autistic disorder pervasive developmental disorder schizophrenia comorbidity 

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REFERENCES

  1. Abikoff, H., & Klein, R. G. (1992). Attention-deficit hyperactivity disorder and conduct disorder: Comorbidity and implications for treatment. Journal of Consulting and Clinical Psychology, 60881-892.Google Scholar
  2. American Psychiatric Association. (1987). Diagnostic and statistical manual of mental disorders, (3rd ed.-Rev.).Washington, DC: Author.Google Scholar
  3. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.)Washington, DC. Author.Google Scholar
  4. Andreasen, N. C. (1984). Scale for the assessment of negative symptoms(SANS). Iowa City: University of Iowa.Google Scholar
  5. Andreasen N. C., & Olsen, S. (1982). Negative and positive schizophrenia: Definition and validation. Archives of General Psychiatry, 39789-707.Google Scholar
  6. Bailey, A., Phillips, W., & Rutter, M. (1996). Autism: Towards an integration of clinical, genetic, neuropsychological and neurobiological perspectives. Journal of Child Psychology and Psychiatry, 3789-126.Google Scholar
  7. Clarke, D. J., Littlejohns, C. S., Gorbett, J. A, & Joseph, S. (1989). Pervasive developmental disorders and psychosis in adult life. British Journal of Psychiatry, 155692-699.Google Scholar
  8. Creak, M. (1963). Childhood psychosis: A review of 100 cases.British Journal of Psychiatry, 10984-89.Google Scholar
  9. DeLisi, L. E. (1992). The significance of age of onset for schizophrenia. Schizophrenia Bulletin, 18(2), 209-215.Google Scholar
  10. Dykens, E., Volkmar, F., & Glick, M. (1991). Thought disorder in high-functioning autistic adults. Journal of Autism and Developmental Disorders, 21291-301.Google Scholar
  11. Goldman, H. H. (1984). Epidemiology. In J. A. Talbott (Ed.), The chronic mental patient: Five years later(pp. 15-30). New York: Grune & Stratton.Google Scholar
  12. Green, W. H., Campbell, M., Hardesty, A. S., Grega, D. M., Padron-Gayol, M., et al.(1984). Journal of the American Academy of Child Psychiatry, 23399-409.Google Scholar
  13. Kolvin, I. (1971) Studies in the childhood psychoses I. Diagnostic criteria and classification. British Journal of Psychiatry, 118381-384.Google Scholar
  14. Kolvin, I., Ounsted, C., Humphrey, M., & McNay, A. (1971) II. The phenomenology of childhood psychoses. British Journal of Psychiatry, 118385-395.Google Scholar
  15. Kolvin, I., Ounsted, C., Richardson, L. M., & Garside, R. F. (1971) III. The family and social background in childhood psychoses, British Journal of Psychiatry, 118396-402.Google Scholar
  16. Konstantareas, M. M., & Homatidis, S. (1989). Assessing child symptom severity and stress in parents of autistic children. Journal of Child Psychology and Psychiatry, 30459-470.Google Scholar
  17. Kraemer, H. C. (1996). Biostatistical recommendations. Journal of Autism and Developmental Disorders, 26150-154.Google Scholar
  18. Le Couteur, A. L., Rutter, M., Lord, C., Rios, P., Robertson, S., Holdrafer, M., & McLennan, J. (1989). Autism Diagnostic Interview-Revised: A standardized investigator-based instrument. Journal of Autism and Developmental Disorders, 19363-387.Google Scholar
  19. Le Couteur, A. L., Phillips, W., & Rutter, M. (1995). A broader phenotype of autism: The clinical spectrum in twins. Journal of Child Psychology and Psychiatry, 37785-801.Google Scholar
  20. Leiter, R. (1969). The Leiter International Performance Scale.Chicago: Stoetling.Google Scholar
  21. Lord, C., Rutter, M., Goode, S., Heemsbergen, J., Jordan, H., Mawood, L., & Schopler, E. (1989). Autism Diagnostic Observation Schedule: A standardized observation of communicative and social behavior. Journal of Autism and Developmental Disorders. 19185-212Google Scholar
  22. McKenna, K., Gordon, C., Lenane, M., Kaysen, D., Fahey, K., & Rapoport, J. (1994). Looking for childhood-onset schizophrenia: The first 71 cases screened. Journal of the American Academy of Child and Adolescent Psychiatry, 33636-644.Google Scholar
  23. Ornitz, E. M. (1969). Disorders of perception common to early infantile autism and schizophrenia. Comprehensive Psychiatry, 10259-274.Google Scholar
  24. Petty, L. K., Ornitz, E. M., Michelman, J. D., & Zimmerman, E. G. (1984) Autistic children who later become schizophrenic. Archives of General Psychiatry, 41129-135.Google Scholar
  25. Pillowsky, T., Yirmiya, N., Shulman, C., & Dover, R. (1998). The Autism Diagnostic Interview-Revised and the Childhood Autism Rating Scale: Differences between diagnostic systems and comparison between genders. Journal of Autism and Developmental Disorders, 28143-151.Google Scholar
  26. Prior, M., & Werry, J. S. (1986). Autism, schizophrenia and allied disorders. In H. C. Quay, & J. S. Werry (Eds.), Psychopathological disorders of childhood(3rd Ed., pp. 156-210). New York: Wiley.Google Scholar
  27. Reiss, S., Levitan, G. W., & Szysko, J. (1982). Emotional disturbance and mental retardation: Diagnostic overshadowing. American Journal of Mental Deficiency, 86567-574.Google Scholar
  28. Rutter, M. (1972). Childhood schizophrenia reconsidered. Journal of Autism and Childhood Schizophrenia, 2315-337.Google Scholar
  29. Rutter, M., & Schopler, E. (1987). Autism and pervasive developmental disorders: Concepts and diagnostic issues. Journal of Autism and Developmental Disorders, 17159-186.Google Scholar
  30. Sherman, M., Nass, R, & Shapiro, T. (1984). Brief report: Regional blood flow in autism. Journal of Autism and Developmental Disorders, 14439-446.Google Scholar
  31. Schopler, E., Reichler, R. J., & Renner, B. R. (1988). The Childhood Autism Rating Scale (CARS).Los Angeles: Western Psychological Services.Google Scholar
  32. Shah, A., & Holmes, N. (1985). Brief report: The use of the Leiter International Performance scale with autistic children. Journal of Autism and Developmental Disorders, 15195-203.Google Scholar
  33. Singh, N. N. & Katz, R. C. (1989). Differential diagnosis in chronic schizophrenia and adult autism. In J. Mason (Ed.), Chronic schizophrenia and adult autism: Issues in diagnosis, assessment and psychological treatment(pp. 163-182). New York: Springer.Google Scholar
  34. Tantam, D. (1988). Asperger's syndrome. Journal of Child Psychology and Psychiatry, 29245-255.Google Scholar
  35. Tsai (1996). Brief report: Comorbid psychiatric disorders of autistic disorder. Journal of Autism and Developmental Disorders, 26159-164.Google Scholar
  36. Waterhouse, L., & Fein, D. (1984). Developmental trends in cognitive skills for children diagnosed as autistic and schizophrenic. Child Development, 55236-248.Google Scholar
  37. Watkins, J. M., Asarnow, R. F., & Tanguay, P. (1988). Symptom development in childhood onset schizophrenia. Journal of Child Psychology and Psychiatry, 29865-878.Google Scholar
  38. Werry, J. S. (1992). Child and adolescent (early onset) schizophrenia: A review in light of the DSM-III-R. Journal of Autism and Developmental Disorders, 22601-624.Google Scholar
  39. Wing, L. (1986). Clarification on Asperger's syndrome. Journal of Autism and Developmental Disorders, 16513-515.Google Scholar
  40. Volkmar, F. R., & Cohen, D. J. (1991). Comorbid association of autism and schizophrenia. American Journal of Psychiatry, 1481705-1707.Google Scholar

Copyright information

© Plenum Publishing Corporation 2001

Authors and Affiliations

  • M. Mary Konstantareas
    • 1
  • Terri Hewitt
    • 2
  1. 1.University of Guelph and Clarke Institute of PsychiatryUSA
  2. 2.Surrey Place CentreToronto

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