Influence of bacteriocin in the control of Escherichia coli infection of broiler chickens in Nigeria

  • S.T. Ogunbanwo
  • A.I. Sanni
  • A.A. Onilude

Abstract

One hundred broiler chickens were divided into four groups. Group A was untreated and challenged with E. coli 02:KH6; group B was infected and treated with bacteriocin in their drinking water; group C was infected and treated by administration of Lactobacillus plantarum F1 culture in skimmed milk, and group D acted as a control. Their weight, feed intake, clinical signs, microscopic lesions, E. coli re-isolation and serum biochemistry were compared. Groups B and C showed fewer symptoms and gross lesions than those from group A, while body weight and feed intakes were similar to the control group. E. coli 02:KH6 was re-isolated in 60% of the livers from group A, compared to 8 and 12% of the livers from group B and C respectively. There was significant increase in the levels of total protein (3.78 ± 0.05 g/100 ml) and globulins (2.53 ± 0.03 g/100 ml) in group A compared to groups B and C. The cholesterol levels in group A (112.56 ± 0.15 mg/100 ml) were significantly reduced compared to those of groups B and C which had 127.25 ± 0.14 and 128.73 ± 0.13 mg/100 ml respectively. The study provides evidence of the potential therapeutic efficacy of bacteriocin in the control of an experimental E. coli infection in broiler chickens.

Bacteriocin broiler chickens L. plantarum probiotics respiratory infection 

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Copyright information

© Kluwer Academic Publishers 2004

Authors and Affiliations

  • S.T. Ogunbanwo
    • 1
  • A.I. Sanni
    • 1
  • A.A. Onilude
    • 1
  1. 1.Department of Botany and MicrobiologyUniversity of IbadanIbadan, Oyo StateNigeria

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