Transition Metal Chemistry

, Volume 29, Issue 1, pp 86–90 | Cite as

Synthesis, spectroscopic characterization and antibacterial activity of lanthanide–tetracycline complexes

  • Gopalakrishnan Karthikeyan
  • Kuttappan Mohanraj
  • Kuppanagounder P. Elango
  • Krishnapillai Girishkumar
Article

Abstract

A series of LnIII–tetracycline complexes of the type [Ln(TC)Cl3]·2H2O [Ln = lanthanum, praseodymium, neodymium, samarium, gadolinium, terbium, dysprosium and yttrium; TC = tetracycline] have been synthesized and characterized by analytical, i.r., electronic, 1H-n.m.r. spectral studies, X-ray diffraction and thermogravimetric analysis. A pentagonal bipyramidal structure has been tentatively proposed for the new complexes. The ligand and the new complexes were tested in vitro to evaluate their activity against the bacteria Escherichia coli and Staphylococcus aureus.

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Copyright information

© Kluwer Academic Publishers 2004

Authors and Affiliations

  • Gopalakrishnan Karthikeyan
    • 1
  • Kuttappan Mohanraj
    • 1
  • Kuppanagounder P. Elango
    • 1
  • Krishnapillai Girishkumar
    • 2
  1. 1.Department of ChemistryGandhigram Rural Institute (Deemed University)GandhigramIndia
  2. 2.Department of Applied ChemistryCochin University of Science and TechnologyCochinIndia

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