An Efficient One-Pot Synthesis of Triamides and Amidodiesters
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- Shaabani, A., Teimouri, M.B. & Bijanzadeh, H.R. Russian Journal of Organic Chemistry (2004) 40: 976. doi:10.1023/B:RUJO.0000045188.81414.1d
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An efficient one-pot procedure has been proposed for the synthesis of compounds containing three carboxamide groups or one carboxamide and two ester groups. The procedure is based on three-component condensation of alkyl isocyanides with 5-alkylidene- or 5-arylmethylene-substituted Meldrum's acids in the presence of such nucleophiles as phenols and amines.
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