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Russian Journal of Genetics

, Volume 40, Issue 6, pp 691–693 | Cite as

Analysis of the Glutathione S-Transferase P1 Gene Ile105Val Polymorphism in the Patients with Sporadic Motor Neuron Disease from Russia

  • A. L. Zherebtsova
  • M. I. Shadrina
  • G. N. Levitsky
  • N. I. Levitskaya
  • A. V. Alekhin
  • P. A. Slominsky
  • V. I. Skvortsova
  • S. A. Limborska
Article

Abstract

Ile105Val polymorphism in exon 5 of glutathione S-transferase (GSTP1) gene was examined in a group of patients with motor neuron disease (MND) and control sample. No statistically significant differences in the allele and genotype frequency distributions between the samples examined were demonstrated. We conclude that Ile105Val polymorphism is not associated with the risk of the disease development in the patients from Russia with sporadic form of MND.

Keywords

Glutathione Control Sample Frequency Distribution Motor Neuron Genotype Frequency 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© MAIK “Nauka/Interperiodica” 2004

Authors and Affiliations

  • A. L. Zherebtsova
    • 1
  • M. I. Shadrina
    • 1
  • G. N. Levitsky
    • 2
  • N. I. Levitskaya
    • 2
  • A. V. Alekhin
    • 2
  • P. A. Slominsky
    • 1
  • V. I. Skvortsova
    • 2
  • S. A. Limborska
    • 1
  1. 1.Institute of Molecular GeneticsRussian Academy of SciencesMoscowRussia
  2. 2.Department of Fundamental and Clinical NeurologyRussian State Medical UniversityMoscowRussia

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