Russian Journal of Genetics

, Volume 40, Issue 3, pp 326–331 | Cite as

Gene Pool Structure of Eastern Ukrainians as Inferred from the Y-Chromosome Haplogroups

  • V. N. Kharkov
  • V. A. Stepanov
  • S. A. Borinskaya
  • Zh. M. Kozhekbaeva
  • V. A. Gusar
  • E. Ya. Grechanina
  • V. P. Puzyrev
  • E. K. Khusnutdinova
  • N. K. Yankovsky


Y chromosomes from representative sample of Eastern Ukrainians (94 individuals) were analyzed for composition and frequencies of haplogroups, defined by 11 biallelic loci located in non-recombining part of the chromosome (SRY1532, YAP, 92R7, DYF155S2, 12f2, Tat, M9, M17, M25,M89, andM56). In the Ukrainian gene, pool six haplogroups were revealed: E, F (including G and I), J, N3, P, and R1a1. These haplogroups were earlier detected in a study of Y-chromosome diversity on the territory of Europe as a whole. The major haplogroup in the Ukrainian gene pool, haplogroup R1a1 (earlier designated HG3), accounted for about 44% of all Y chromosomes in the sample examined. This haplogroup is thought to mark the migration patterns of the early Indo-Europeans and is associated with the distribution of the Kurgan archaeological culture. The second major haplogroup is haplogroup F (21.3%), which is a combination of the lineages differing by the time of appearance. Haplogroup P found with the frequency of 9.6%, represents the genetic contribution of the population originating from the ancient autochthonous population of Europe. Haplogroups J and E (11.7 and 4.2%, respectively) mark the migration patterns of the Middle-Eastern agriculturists during the Neolithic. The presence of the N3 lineage (9.6%) is likely explained by a contribution of the assimilated Finno–Ugric tribes. The data on the composition and frequencies of Y-chromosome haplogroups in the sample studied substantially supplement the existing picture of the male lineage distribution in the Eastern Slav population.


Representative Sample Gene Pool Migration Pattern Genetic Contribution Lineage Distribution 
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Copyright information

© MAIK “Nauka/Interperiodica” 2004

Authors and Affiliations

  • V. N. Kharkov
    • 1
  • V. A. Stepanov
    • 1
  • S. A. Borinskaya
    • 2
  • Zh. M. Kozhekbaeva
    • 2
  • V. A. Gusar
    • 3
  • E. Ya. Grechanina
    • 3
  • V. P. Puzyrev
    • 1
  • E. K. Khusnutdinova
    • 4
  • N. K. Yankovsky
    • 2
  1. 1.Institute of Medical Genetics, Tomsk Research CenterRussian Academy of Medical SciencesTomskRussia
  2. 2.Vavilov Institute of General GeneticsRussian Academy of SciencesMoscowRussia
  3. 3.Kharkov Inter-Regional Center for Medical Genetics and Prenathal DiagnosticsKharkovUkraine
  4. 4.Institute of Biochemistry and Genetics, Ufa Research CenterRussian Academy of Sciences, UfaBashkortostanRussia

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