Russian Journal of Bioorganic Chemistry

, Volume 30, Issue 4, pp 367–373 | Cite as

Elucidation of Structure of Lipid A from the Marine Gram-Negative Bacterium Pseudoalteromonas haloplanktis ATCC 14393T

  • I. N. Krasikova
  • N. V. Kapustina
  • V. V. Isakov
  • N. M. Gorshkova
  • T. F. Solov'eva
Article

Abstract

The chemical structure of lipid A, from the marine γ-proteobacterium Pseudoalteromonashaloplanktis АТСС 14393Т, a main product of lipopolysaccharide hydrolysis (1% AcOH), was determined using chemical methods and NMR spectroscopy. The lipid A was shown to be β-1,6-glucosaminobiose 1,4′-diphosphate acylated with two (R)-3-hydroxyalkanoic acid residues at C3 and C3′ and amidated with one (R)-3-hydroxydodecanoyl and one (R)-3-dodecanoyloxydodecanoyl residue at N2 and N2′, respectively.

1H 31P 13C NMR spectroscopy lipid A lipopolysaccharide marine Gram-negative bacterium Pseudoalteromonas haloplanktis 

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Copyright information

© MAIK “Nauka/Interperiodica” 2004

Authors and Affiliations

  • I. N. Krasikova
  • N. V. Kapustina
    • 1
  • V. V. Isakov
    • 1
  • N. M. Gorshkova
    • 1
  • T. F. Solov'eva
    • 1
  1. 1.Pacific Institute of Bioorganic ChemistryFar Eastern Division, Russian Academy of Sciences, prStoletiya VladivostokaRussia

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