Pharmaceutical Research

, Volume 21, Issue 11, pp 2133–2134 | Cite as

Transporter Database, TP-Search: A Web-Accessible Comprehensive Database for Research in Pharmacokinetics of Drugs

  • Naoki Ozawa
  • Takako Shimizu
  • Rika Morita
  • Yoshiya Yokono
  • Takafumi Ochiai
  • Kiyotaka Munesada
  • Akira Ohashi
  • Yoshitaka Aida
  • Yoshimasa Hama
  • Katsuhiko Taki
  • Kazuya Maeda
  • Hiroyuki Kusuhara
  • Yuichi Sugiyama
Letter to the Editor

REFERENCES

  1. 1.
    R. B. Kim. Transporters in drug disposition. Curr. Opin. Drug Discov. Devel. 3:94–101 (2000).Google Scholar
  2. 2.
    V. H. Lee, J. L. Sporty, and T. E. Fandy. Pharmacogenomics of drug transporters: the next drug delivery challenge. Adv. Drug Deliv. Rev. 50:S33–S40 (2001).PubMedGoogle Scholar
  3. 3.
    A. Ayrton and P. Morgan. Role of transport proteins in drug absorption, distribution and excretion. Xenobiotica 31:469–497 (2001).PubMedGoogle Scholar
  4. 4.
    H. Kusuhara and Y. Sugiyama. Role of transporters in the tissue-selective distribution and elimination of drugs: transporters in the liver, small intestine, brain and kidney. J. Controlled Release 78: 43–54 (2002).Google Scholar
  5. 5.
    Q. Yan and W. Sadée. Human membrane transporter database: A web-accessible relational database for drug transport studies and pharmacogenomics. AAPS Pharmsci. 2:1–7 (2000).Google Scholar
  6. 6.
    L. Z. Ji Sun, X. Chen, J. F. Wang, and Y. Z. Chen. ADME-AP: a database of ADME associated proteins. Bioinformatics 18: 1699–1700 (2002).PubMedGoogle Scholar
  7. 7.
    H. Suzuki and Y. Sugiyama. Role of metabolic enzymes and ef-flux transporters in the absorption of drugs from the small intes-tine. Eur. J. Pharm. Sci. 12:3–12 (2000).PubMedGoogle Scholar
  8. 8.
    V. J. Wacher, L. Salphati, and L. Z. Benet. Active secretion and enterocytic drug metabolism barriers to drug absorption. Adv. Drug Deliv. Rev. 46:89–102 (2001).PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2004

Authors and Affiliations

  • Naoki Ozawa
    • 1
    • 2
  • Takako Shimizu
    • 2
  • Rika Morita
    • 2
  • Yoshiya Yokono
    • 2
  • Takafumi Ochiai
    • 2
  • Kiyotaka Munesada
    • 2
  • Akira Ohashi
    • 2
  • Yoshitaka Aida
    • 2
  • Yoshimasa Hama
    • 2
  • Katsuhiko Taki
    • 3
  • Kazuya Maeda
    • 4
  • Hiroyuki Kusuhara
    • 4
  • Yuichi Sugiyama
    • 4
  1. 1.Wyeth K.K.Tokyo
  2. 2.Advanced Research Institute for Science and EngineeringWaseda UniversityTokyo
  3. 3.Nihon Visual Science, Inc.Tokyo
  4. 4.Graduate School of Pharmaceutical ScienceThe University of TokyoTokyo

Personalised recommendations