Neuropsychology Review

, Volume 14, Issue 1, pp 1–41 | Cite as

Clinical Implications and Methodological Challenges in the Study of the Neuropsychological Correlates of Cannabis, Stimulant, and Opioid Abuse

  • Antonio Verdejo-García
  • Francisca López-Torrecillas
  • Carmen Orozco Giménez
  • Miguel Pérez-García
Article

Abstract

Chronic consumption of several drugs of abuse (cannabis, stimulants, opioids) has been associated with the presence of neuropsychological impairments in a broad range of functions. Nevertheless, in recent years neuropsychological research on substance abuse has focused on the study of impairments in the executive functions linked to the prefrontal cortex and their influence on the personality, cognitions, and behaviors of the substance abusers. The aim of our review is, first, to summarize the main neuropsychological impairments shown by classic studies, as well as these new discoveries in executive functioning; second, to consider the mediating role of neuropsychological status on treatment outcomes and analyze the impact of these impairments in clinical practice with drug addicts; and third, to review the principal methodological challenges associated with research in the field of the neuropsychology of substance abuse. We also highlight the convenience of intervening in those functions most relevant to the abusers' persistence in consumption and risk of relapse.

substance abuse neuropsychological impairment executive functioning clinical relevance recoverability methodological challenges 

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Copyright information

© Plenum Publishing Corporation 2004

Authors and Affiliations

  • Antonio Verdejo-García
    • 1
  • Francisca López-Torrecillas
    • 1
  • Carmen Orozco Giménez
    • 1
  • Miguel Pérez-García
    • 1
  1. 1.Departamento de Personalidad, Evaluación y Tratamiento PsicológicoUniversidad de GranadaGranadaSpain

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