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Mycopathologia

, Volume 157, Issue 2, pp 185–189 | Cite as

Antimicrobial Activities of Selected Cyathus Species

  • Ya-Jun Liu
  • Ke-Qin Zhang
Article

Abstract

Twelve selected Cyathus species were tested for their abilities to produce antimicrobial metabolites. Most of them were found to produce secondary exo-metabolites that could induce morphological abnormalities of rice pathogenic fungi Pyricularia oryzae. Some extracts from the cultivated liquid obviously inhibited human pathogenic fungi Aspergillus fumigatus, Candida albicans and Cryptococcus neoformans. Activities against six human pathogenic bacteria were also obtained from some of these extracts.

active metabolites Bird's nest fungi morphological abnormalities 

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References

  1. 1.
    Alexopoulos CJ, Mims CW, Blackwell M. Introductory Mycology, 4th edn. New York: John Wiley & Sons, 1996: 488.Google Scholar
  2. 2.
    Albutt AD, Ayer WA, Brodie HJ, Johri BN, Taube H. Cyathin, a new antibiotic complex produced by Cyathus helenae. Can J Microbiol 1971; 17: 1401.Google Scholar
  3. 3.
    Ayer WA, Ttaube H. Metabolites of Cyathus helenae: a new class of diterpenoids. Can J Chem 1973; 51: 3842–3854.Google Scholar
  4. 4.
    Ayer WA, Taylor DR. Metabolites of the Bird's Nest Fungi. Part 5. The isolation of 1-hydroxy-6-methyl-8-hydroxymethylxanthone, a new xanthone from Cyathus intermedius synthesis via photoenolisation. Can J Chem 1976; 54: 1703–1707.Google Scholar
  5. 5.
    Anke T, Oberwinkler F, Steglich W, Holfe G. The striatins: new antibiotics from the basidiomycete Cyathus striatus (Huds ex. Pers) willd. J Antibiotics 1977; 30: 221–225.Google Scholar
  6. 6.
    Ayer WA, Yoshida T, van Schie DMJ. Metabolites of Birds Nest Fungi. 9. Diterpenoid metabolites of Cyatus africanus. Can J Chem 1978; 56: 2113–2120.Google Scholar
  7. 7.
    Ayer WA, Lee SP. Metabolites of the Bird's Nest Fungi. Part 11. Diterpenoid metabolites of Cyathus earlei Lloyd. Can J Chem 1979; 57: 3332–3337.Google Scholar
  8. 8.
    Ayer WA, Paice MG. Metabolites of the Bird's Nest Fungi. Part 4. The isolation and structure determination of cybullol, a metabolite of Cyathus bulleri Brodie. Can J Chem 1976; 54: 910–916.Google Scholar
  9. 9.
    Ayer WA, McCaskill RH. The cybrodins, a new class of sesquiterpenes. Can J Chem 1981; 59(14): 2150–2158.Google Scholar
  10. 10.
    Ayer WA, McCaskill RH. Bullerone, A novel sesquiterpenoid from Cyathus bulleri Brodie. Can J Chem 1987; 65(1): 15–17.Google Scholar
  11. 11.
    Kobayashi H. Namikoshi M, Yoshimoto T. A screening method for antimitotic and antifungal substances using conidia of Pyricularia oryzae, modification and application to tropical marine fungi. J Antibiotics 1996; 49: 873–879.Google Scholar
  12. 12.
    Gunji S, Arima K, Beppu T. Screening of antifungal antibiotics according to activities inducing morphological abnormalities. Agric Boil Chem 1983; 47(9): 2061–2069.Google Scholar
  13. 13.
    Barathora H, Betina V, Nemec P. Morphological changes induced in fungi by antibiotics. Folia Microbiol 1969; 14: 475–483.Google Scholar
  14. 14.
    Richmond DV. Effect of toxicants on the morphology and fine structure of fungi. Adv Appl Microbiol 1975; 19: 289–319.PubMedGoogle Scholar
  15. 15.
    White RJ. Microbiological model as screening tools for anticancer agents: potentials and limitations. Ann Rev Microbiol 1982; 36: 415–433.Google Scholar

Copyright information

© Kluwer Academic Publishers 2004

Authors and Affiliations

  1. 1.Key Laboratory for Conservation and Utilization of Bio-resourceYunnan UniversityKunming, YunnanP.R. China

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