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Journal of Chemical Ecology

, Volume 29, Issue 12, pp 2781–2786 | Cite as

A Siphonotid Millipede (Rhinotus) as the Source of Spiropyrrolizidine Oximes of Dendrobatid Frogs

  • R. A. Saporito
  • M. A. Donnelly
  • R. L. Hoffman
  • H. M. Garraffo
  • J. W. Daly
Article

Abstract

Poison frogs of the neotropical family Dendrobatidae contain a wide variety of lipophilic alkaloids, which are accumulated from alkaloid-containing arthropods. A small millipede, Rhinotus purpureus (Siphonotidae), occurs microsympatrically with the dendrobatid frog Dendrobates pumilio on Isla Bastimentos, Bocas del Toro Province, Panamá. Methanol extracts of this millipede contain the spiropyrrolizidine O-methyloxime 236, an alkaloid previously known only from skin extracts of poison frogs, including populations of D. pumilio. Thus, R. purpureus represents a likely dietary source of such alkaloids in dendrobatid frogs.

Alkaloids arthropods frogs dendrobatids millipedes pyrrolizidines 

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Copyright information

© Plenum Publishing Corporation 2003

Authors and Affiliations

  • R. A. Saporito
    • 1
  • M. A. Donnelly
    • 1
  • R. L. Hoffman
    • 2
  • H. M. Garraffo
    • 3
  • J. W. Daly
    • 3
  1. 1.Department of Biological SciencesFlorida International UniversityMiami
  2. 2.Virginia Museum of Natural HistoryMartinsville
  3. 3.Laboratory of Bioorganic ChemistryNational Institute of Diabetes and Digestive, and Kidney Diseases, NIH, DHHSBethesda

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