Fish Physiology and Biochemistry

, Volume 28, Issue 1–4, pp 327–328 | Cite as

Interactions of calcium and cyclic AMP signaling pathways regulating steroidogenesis in primary cultured theca and granulosa cells of Atlantic croaker

  • A.D. Benninghoff
  • P. Thomas


The function of adenylyl cyclase (AC)-dependent and calcium (Ca2+)-dependent signal transduction pathways in mediating gonadotropin-stimulated testosterone (T) synthesis in croaker follicular cells was investigated. Both pathways are critical regulators of steroidogenesis in these cells. Stimulation of steroidogenesis by modulators of AC-dependent cell signaling is partially dependent on the presence of extracellular Ca2+, although AC function does not appear to be mediated by the Ca2+ pathway in croaker follicular cells.

calcium adenylyl cyclase fish steroidogenesis testosterone 


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Copyright information

© Kluwer Academic Publishers 2003

Authors and Affiliations

  • A.D. Benninghoff
    • 1
  • P. Thomas
    • 1
  1. 1.Marine Science InstituteUniversity of Texas at AustinPort AransasUSA

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