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Digestive Diseases and Sciences

, Volume 49, Issue 4, pp 680–687 | Cite as

Quality of Life in Patients with Subjective Food Hypersensitivity: Applicability of the 10-Item Short Form of the Nepean Dyspepsia Index

  • Gülen Arslan
  • Ragna Lind
  • Snorri Olafsson
  • Erik Florvaag
  • Arnold Berstad
Article

Abstract

The aim of this study was to investigate quality of life and applicability of the 10-item short form of the Nepean Dyspepsia Index (SF-NDI) in patients with subjective food hypersensitivity. Fifty-two adult patients and 120 controls were examined using three questionnaires: Quality of life Nepean Dyspepsia Index (NDI), Gastrointestinal Symptom Rating Scale (GSRS), and Ulcer Esophagitis Subjective Symptoms Scale (UESS). To document psychometric properties, 20 of the patients filled in the SF-NDI questionnaire once more 4 weeks later. Patients had poor quality of life compared with controls from health care workers or general population (P < 0.001). Scores on SF-NDI were significantly correlated with scores on the GSRS (r = 0.34, P = 0.02) and UESS (r = 0.41, P = 0.003). The SF-NDI performed very satisfactorily, with a high reliability, construct validity, and responsiveness. Patients with subjective food hypersensitivity have considerably reduced quality of life. The SF-NDI provides reliable, responsive, and clinically valid measures of quality of life in these patients.

food hypersensitivity quality of life reliability validity responsiveness 

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References

  1. 1.
    O'Leary PFG, Shanahan F: Food allergies. Curr Gastroenterol Rep 4:373-382, 2002Google Scholar
  2. 2.
    Young E, Stoneham MD, Petruckevitch A, Barton J, Rona R: A population study of food intolerance. Lancet 343(2):1127-1130, 1994Google Scholar
  3. 3.
    Jansen JJ, Kardinaal AF, Huijbers G, Vlieg-Boerstra BJ, Martens BP, Ockhuizen T: Prevalence of food allergy and intolerance in the adult Dutch population. J Allergy Clin Immunol 93(2):446-456, 1994Google Scholar
  4. 4.
    Agreus L: Natural history of dyspepsia. Gut 50 (Suppl IV):2-9, 2002Google Scholar
  5. 5.
    Leynaert B, Soussan D: Monitoring the quality of life in allergic disorders. Curr Opin Allergy Clin Immunol 3:177-183, 2003Google Scholar
  6. 6.
    Sicherer SH, Noone SA, Munoz-Furlong A: The impact of childhood food allergy on quality of life. Ann Allergy Asthma Immunol 87:461-464, 2001Google Scholar
  7. 7.
    Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner SA: Functional bowel disorders and functional abdominal pain. Gut 45 (Suppl II): 43-47, 1999Google Scholar
  8. 8.
    Glise H, Hallerbäck B, Wiklund I: Quality of life: a reflection of symptoms and concerns. Scand J Gastroenterol 31 (Suppl 221):14-17, 1996Google Scholar
  9. 9.
    Shaw M, Talley NJ, Adlis S, Beebe T, Tomshine P, Healey M: Development of a digestive health status instrument: tests of scaling assumptions, structure and reliability in a primary care population. Aliment Pharmacol Ther 12:1067-1078, 1998Google Scholar
  10. 10.
    Talley NJ, Verlinden M, Jones M: Validity of a new quality of life scale for functional dyspepsia: A united states multicenter trial of the Nepean Dyspepsia Index. Am J Gastroenterol 94:2390-2397, 1999Google Scholar
  11. 11.
    Talley NJ, Verlinden M, Jones M: Quality of life in functional dyspepsia: responsiveness of the Nepean Dyspepsia Index and development of a new 10-items short form. Aliment Pharmacol Ther 15: 207-216, 2001Google Scholar
  12. 12.
    Bindslev-Jensen C: Standardization of double-blind, placebo-controlled food challenges. Allergy 56 (Suppl 67):75-77, 2001Google Scholar
  13. 13.
    Rustø;en T, Wiklund I, Hanestad BR, Burckhardt CS: Validity and reliability of the Norwegian version of the Ferrans and Powers quality of life index. Scand J Caring Sci 13:96-101, 1999Google Scholar
  14. 14.
    Olafsson S, Berstad A: Changes in food tolerance and lifestyle after eradication of Helicobacter pylori. Scand J Gastroenterol 38:268-276, 2003Google Scholar
  15. 15.
    Olafsson S, Hatlebakk JG, Berstad A: Patients with endoscopic gastritis and/or duodenitis improve markedly following eradication of Helicobacter pylori, although less so than patients with ulcers. Scand J Gastroenterol 37:1386-1394, 2002Google Scholar
  16. 16.
    Dimenäs E, Glise H, Hallerbäck B, Hernqvist H, Svedlund J, Wiklund I: Quality of life in patients with upper gastrointestinal symptoms. An improved evaluation of treatment regimens?. Scand J Gastroenterol 28:681-687, 1993Google Scholar
  17. 17.
    Svedlund J, Sjø;din I, Dotevall G: GSRS-A clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease. Dig Dis Sci 33:129-134, 1988Google Scholar
  18. 18.
    Bland JM, Altman DG: Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 8:307-310, 1986Google Scholar
  19. 19.
    Guyatt GH, Feeny DH, Patrick DL: Measuring health-related quality of life. Ann Intern Med 118:622-629, 1993Google Scholar
  20. 20.
    Agreus L, Svardsudd K, Nyren O, Tibblin G: The epidemiology of abdominal symptoms: prevalence and demographic characteristics in a Swedish adult population. A report from the Abdominal Symptom Study. Scand J Gastroenterol 29:102-109, 1994Google Scholar
  21. 21.
    Vatn MH, Grimstad IA, Thorsen L, Kittang E, Refnin I, Malt U, Lø;vik A, Langeland T, Naalsund A. Adverse reaction to food: assessment by double-blind placebo controlled food challenge and clinical, psychosomatic and immunologic analysis. Digestion 56:421-428, 1995Google Scholar
  22. 22.
    Weidenhiller M, Tränkner A, Schwab D, Winterkamp S, Hahn EG, Raithel M: Different kinetics of mediator release can be detected during allergic reactions after oral provocation (double blind placebo-controlled food challenge). Inflamm Res 51 (Supp I): S29-S30, 2002Google Scholar
  23. 23.
    Eriksen RH, Ursin H: Sensitization and subjective health complaints. Scand J Psychol 43:189-196, 2002Google Scholar
  24. 24.
    Johansen SGO, Hourihane JOB, Bousquet J, Bruijnzeel-Koomen C, Dreborg S, Haahtela T, Kowalski ML: A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force. Allergy 56:813-824, 2001Google Scholar
  25. 25.
    Simren M, Maansson A, Langkilde AM, Svedlund J, Abrahamsson H, Bengtsson U, Bjornsson ES: Food-related gastrointestinal symptoms in the irritable bowel syndrome. Digestion 63:108-115, 2001Google Scholar
  26. 26.
    Talley NJ, Weaver AL, Zinsmeister AR: Impact of functional dyspepsia on quality of life. Dig Dis Sci 40:584-589, 1995Google Scholar
  27. 27.
    Whitehead WE, Burnett CK, Cook EW, Taub E: Impact of irritable bowel syndrome on quality of life. Dig Dis Sci 41:2248-2253, 1996Google Scholar
  28. 28.
    Garratt AM, Ruta DA, Russell I, Macleod K, Brunt P, McKinlay A, Mowat A, Sinclair T: Developing a condition-specific measure of health for patients with dyspepsia and ulcer-related symptoms. J Clin Epidemiol 49:565-571, 1996Google Scholar
  29. 29.
    Andersson P, Olaison G, Bendtsen P, Myrelid P, Sjodahl R: Health related quality of life in Crohn's proctocolitis does no differ from a general population when in remission. Colorectal Dis 5:56-62, 2003Google Scholar
  30. 30.
    Bender BG: Measurement of quality of life in pediatric asthma clinical trials. Ann Allergy Asthma Immunol 77:438-437, 1996Google Scholar
  31. 31.
    Herd RM, Tidman MJ, Ruta DA, Hunter JAA: Measurement of quality of life in atopic dermatitis: correlation and validation of two different methods. Br J Dermatol 136:502-507, 1997Google Scholar

Copyright information

© Plenum Publishing Corporation 2004

Authors and Affiliations

  • Gülen Arslan
    • 1
    • 2
  • Ragna Lind
    • 1
  • Snorri Olafsson
    • 1
  • Erik Florvaag
    • 3
  • Arnold Berstad
    • 1
  1. 1.Division of GastroenterologyInstitute of MedicineBergenNorway
  2. 2.National Institute of Nutrition and Seafood ResearchBergenNorway
  3. 3.Laboratory of Clinical Biochemistry, Centre for Occupational and Environmental AllergyHaukeland University HospitalBergenNorway

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