Cancer Causes & Control

, Volume 14, Issue 10, pp 907–914 | Cite as

Occupation and bladder cancer among men in Western Europe

  • Manolis Kogevinas
  • Andrea 't Mannetje
  • Sylvaine Cordier
  • Ulrich Ranft
  • Carlos A. González
  • Paolo Vineis
  • Jenny Chang-Claude
  • Elsebeth Lynge
  • Jürgen Wahrendorf
  • Anastasia Tzonou
  • Karl-Heinz Jöckel
  • Consol Serra
  • Stefano Porru
  • Martine Hours
  • Eberhard Greiser
  • Paolo Boffetta
Article

Abstract

Objectives: We examined which occupations and industries are currently at high risk for bladder cancer in men. Methods: We combined data from 11 case–control studies conducted between 1976–1996 in six European countries. The study comprised 3346 incident cases and 6840 controls, aged 30–79 years. Lifetime occupational and smoking histories were examined using common coding. Results: Odds ratios for eight a priori defined high-risk occupations were low, and with the exception of metal workers and machinists (OR = 1.16, 95% CI = 1.02–1.32), were not statistically significant. Higher risks were observed for specific categories of painters, metal, textile and electrical workers, for miners, transport operators, excavating-machine operators, and also for non-industrial workers such as concierges and janitors. Industries entailing a high risk included salt mining, manufacture of carpets, paints, plastics and industrial chemicals. An increased risk was found for exposure to PAHs (OR for highest exposure tertile = 1.23, 95% CI = 1.07–1.4). The risk attributable to occupation ranged from 4.2 to 7.4%, with an estimated 4.3% for exposure to PAHs. Conclusions: Metal workers, machinists, transport equipment operators and miners are among the major occupations contributing to occupational bladder cancer in men in Western Europe. In this population one in 10 to one in 20 cancers of the bladder can be attributed to occupation.

bladder neoplasms occupation 

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Copyright information

© Kluwer Academic Publishers 2003

Authors and Affiliations

  • Manolis Kogevinas
    • 1
    • 2
  • Andrea 't Mannetje
    • 3
  • Sylvaine Cordier
    • 4
  • Ulrich Ranft
    • 5
  • Carlos A. González
    • 6
  • Paolo Vineis
    • 7
  • Jenny Chang-Claude
    • 8
  • Elsebeth Lynge
    • 9
  • Jürgen Wahrendorf
    • 8
  • Anastasia Tzonou
    • 10
  • Karl-Heinz Jöckel
    • 11
  • Consol Serra
    • 12
    • 13
  • Stefano Porru
    • 14
  • Martine Hours
    • 15
  • Eberhard Greiser
    • 16
  • Paolo Boffetta
    • 3
  1. 1.Respiratory and Environmental Health Research UnitMunicipal Institute of Medical Research (IMIM)BarcelonaSpain
  2. 2.Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and GeneticsNational Cancer InstituteBethesdaUSA
  3. 3.International Agency for Research on CancerLyonFrance
  4. 4.INSERM U435Université de Rennes IFrance
  5. 5.Institut für Umweltmedizinische Forschung (IUF), Heinrich-Heine-UniversitätDüsseldorfGermany
  6. 6.Department of Epidemiology Catalan Institute of OncologyBarcelonaSpain
  7. 7.Unit of Cancer EpidemiologyUniversity of TurinItaly
  8. 8.Deutsches KrebsforschungszentrumAbteilung EpidemiologieHeidelbergGermany
  9. 9.Institute of Public HealthUniversity of CopenhagenDenmark
  10. 10.Department of Hygiene and EpidemiologyMedical School of AthensAthensGreece
  11. 11.Institut für Medizinische Informatik, Biometrie und Epidemiologie, EssenGermany
  12. 12.Corporació Parc TaulíSabadellSpain
  13. 13.Pompeu Fabra UniversityBarcelonaSpain
  14. 14.Institute of Occupational HealthUniversity of BresciaItaly
  15. 15.Institut d'ÉpidémiologieUniversité Claude BernardLyonFrance
  16. 16.Bremen Institute for Prevention Research and Social MedicineBremenGermany

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