Biotechnology Letters

, Volume 26, Issue 6, pp 463–472 | Cite as

Applied biocatalysis for the synthesis of natural flavour compounds – current industrial processes and future prospects

  • J. Schrader
  • M.M.W. Etschmann
  • D. Sell
  • J.-M. Hilmer
  • J. Rabenhorst


The industrial application of biocatalysis for the production of natural flavour compounds is illustrated by a discussion of the production of vanillin, γ-decalactone, carboxylic acids, C6 aldehydes and alcohols (`green notes'), esters, and 2-phenylethanol. Modern techniques of molecular biology and process engineering, such as heterologous expression of genes, site-directed mutagenesis, whole-cell biocatalysis in biphasic systems, and cofactor regeneration for in vitro oxygenation, may result in more biocatalytic processes for the production of flavour compounds in the future.

biocatalysis γ-decalactone flavour 2-phenylethanol vanillin 


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Copyright information

© Kluwer Academic Publishers 2004

Authors and Affiliations

  • J. Schrader
    • 1
  • M.M.W. Etschmann
    • 1
  • D. Sell
    • 1
  • J.-M. Hilmer
    • 2
  • J. Rabenhorst
    • 2
  1. 1.Karl Winnacker Institute, DECHEMA e.V.Frankfurt/MainGermany
  2. 2.Symrise GmbH & Co. KGHolzmindenGermany

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