Digestive Diseases and Sciences

, Volume 44, Issue 8, pp 1626–1631 | Cite as

Case Report: An Autopsy Case of Malignant Mesothelioma with Osseous and Cartilaginous Differentiation (Bone Morphogenetic Protein-2 in Mesothelial Cells and Its Tumor)

  • Yasuhiko Kiyozuka
  • Hiroaki Miyazaki
  • Katsuhiko Yoshizawa
  • Hideto Senzaki
  • Daigo Yamamoto
  • Kyoichi Inoue
  • Kazuhisa Bessho
  • Yasunori Okubo
  • Kenji Kusumoto
  • Airo Tsubura
Article
BONE MORPHOGENETIC PROTEIN-2 MALIGNANT MESOTHELIOMA CARTILAGE OSSEOUS DIFFERENTIATION RT-PCR AUTOPSY 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

REFERENCES

  1. 1.
    Attanoos RL, Gibbs AR: Pathology of malignant mesothelioma. Histopathology 30:403–418, 1997Google Scholar
  2. 2.
    Bolen JW, Hammar SP, McNutt MA: Reactive and neoplasticse rosal tissue. Am J Surg Pathol 10:34–47, 1986Google Scholar
  3. 3.
    Stout AP, Murray MR: Localized pleural mesothelioma: Investigation of its characteristics and histogenesis by the method of tissue culture. Arch Pathol 34:951–964, 1942Google Scholar
  4. 4.
    Goldstein B: Two malignant pleural mesotheliomas with unusual histological features. Thorax 34:375–379, 1979Google Scholar
  5. 5.
    Campbell GD, Greenberg SD: Pleural mesothelioma with calcified liver metastases. Chest 79:229–230, 1981Google Scholar
  6. 6.
    McCaughey WTE: Primary tumors of the pleura. J Pathol Bacteriol 76:517–529, 1958Google Scholar
  7. 7.
    Persaud V, Bateson EM, Bankay CD: Pleural mesothelioma associated with massive hepatic calcification and unusual me-tastases. Cancer 26:920–928, 1970Google Scholar
  8. 8.
    Yoshii C, Imai S, Hoshino H, Sugaya H, Mizutani Y, Iwaki H, Enomoto K: A case of malignant pleural mesothelioma with osseous and cartilaginous formation. Jpn J Thorac Dis 30:338–342, 1992Google Scholar
  9. 9.
    Yousem SA, Hochholzer L: Malignant mesotheliomas with osseous and cartilaginous differentiation. Arch Pathol Lab Med 111:62–66, 1987Google Scholar
  10. 10.
    Urist MR: Bone: Formation by autoinduction. Science 150:893–899, 1965Google Scholar
  11. 11.
    Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whitters MJ, Kriz RW, Hewick RM, Wang EA: Novel regulators of bone formation: Molecular clones and activities. Science 242:1528–1534, 1988Google Scholar
  12. 12.
    Wozney JM: The bone morphogenetic protein family and osteogenesis. Mol Reprod Dev 32:160–167, 1992Google Scholar
  13. 13.
    Cunningham NS, Paralkar V, Reddi AH: Osteogenin and recombinant bone morphogene tic protein 2B are chemotactic for human monocyte s and stimulate transforming growth factor beta 1 mRNA expression. Proc Natl Acad Sci USA 89:11740–11744, 1992Google Scholar
  14. 14.
    Hogan BL: Bone morphogenetic proteins: Multifunctional regulators of vertebrate development. Genes Dev 10:1580–1594, 1996Google Scholar
  15. 15.
    Lind M, Eriksen EF, Bunger C: Bone morphogenetic protein-2 but not bone morphogenetic protein-4 and-6 stimulates che-motactic migration of human osteoblasts, human marrow osteoblasts, and U2-OS cells. Bone 18:53–57, 1996Google Scholar
  16. 16.
    Paralkar VM, Weeks BS, Yu YM, Kleinman HK, Reddi AH: Recombinant human bone morphogenetic protein 2B stimulates PC12 cell differentiation: Potentiation and binding to type IV collagen. J Cell Biol 119:1721–1728, 1992Google Scholar
  17. 17.
    Ozkaynak E, Schnegelsberg PNJ, Oppermann H: Murine osteogenic protein (OP-1): High levels of mRNA in kidney. Biochem Biophys Res Commun 179:116–123, 1991Google Scholar
  18. 18.
    Hatakeyama S, Gao YH, Ohara-Nemoto Y, Kataoka H, Satoh M: Expression of bone morphogenetic proteins of human neoplastic epithelial cells. Biochem Mol Biol Int 42:497–505, 1997Google Scholar
  19. 19.
    Rogers MB, Rosen V, Wozney JM, Gudas LJ: Bone morphogenetic proteins-2 and-4 are involved in there tinoic acidinduced differentiation of embryonal carcinoma cells. Mol Biol Cell 3:189–196, 1992Google Scholar
  20. 20.
    Hatakeyama S, Ohara-Nemoto Y, Kyakumoto S, Satoh M: Expression of bone morphogene tic protein in human adenocarcinoma cell line. Biochem Biophys Res Commun 190:695–701, 1993Google Scholar
  21. 21.
    Ogase A, Motoyama T, Hotta T, Watanabe H: Expression of bone morphogenetic proteins in human osteogenic and epithelial tumor cells. Pathol Int 46:9–14, 1996Google Scholar
  22. 22.
    Dale L, Howes G, Price BMJ, Smith JC: Bone morphogenetic protein 4: A centralizing factor in early Xenopus development. Development 115:573–585, 1992Google Scholar
  23. 23.
    Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156–159, 1987Google Scholar
  24. 24.
    Ide H, Yoshida T, Matsumoto N, Aoki K, Osada Y, Sugimura T, Terada M: Growth regulation of human prostate cancer cells by bone morphogenetic protein-2. Cancer Res 57:5022–5027, 1997Google Scholar
  25. 25.
    Morales DE, McGowan KA, Grant DS, Maheshwari S, Bhartiya D, Cid MC, Kleinman HK, Schnaper HW: Estrogen promotes angiogenic activity in human umbilical vein endothelial cells in vitro and in murine model. Circulation 91:755–762, 1995Google Scholar
  26. 26.
    Burns TR, Greenberg D, Mace ML, Johnson EH: Ultrastructural diagnosis of epithelial malignant mesothelioma. Cancer 56:2036–2040, 1985Google Scholar
  27. 27.
    Coleman M, Henderson DW, Muhkerjee TM: The ultrastructural pathology of malignant pleural mesothelioma. Pathol Annu 24:303–353, 1989Google Scholar
  28. 28.
    Dejmek A: Methods to improve the diagnostic accuracy of malignant mesothelioma. Respir Med 90:191–199, 1996Google Scholar
  29. 29.
    Holden J, Churg A: Immunohistochemical staining for keratin and carcinoembryonic antigen in the diagnosis of malignant mesothelioma. Am J Surg Pathol 8:277–279, 1984Google Scholar
  30. 30.
    Sheibani K, Esteban JM, Bailey A, Battifora H, Weiss LM: Immunopathologic and molecular studies as an aid to the diagnosis of malignant mesothelioma. Hum Pathol 23:107–116, 1992Google Scholar
  31. 31.
    Davis JMG: Histogenesis and fine structure of peritoneal tumors produced in animals by injections of asbestos. J Natl Cancer Inst 52:1823–1837, 1974Google Scholar
  32. 32.
    Perks WH, Crow JC, Green M: Mesothelioma associated with the syndrome of inappropriate secretion of antidiuretic hormone. Am Rev Respir Dis 117:789–794, 1978Google Scholar
  33. 33.
    Wozney JM: Bone morphogenetic proteins and their gene expression. In Cellular and Molecular Biology of Bone. M Noda (ed). San Diego, Academic Press, 1993, pp 131–167Google Scholar
  34. 34.
    Wang EA, Rosen V, D'Alessandro JS, Bauduy M, Cordes P, Harada T, Israel DI, Hewick RM, Kerns KM, LaPan P, Luxenberg DP, McQuaid D, Moutsatsos IK, Nove J, Wozney JM: Recombinant human bone morphogenetic protein induces bone formation. Proc Natl Acad Sci USA 87:2220–2224, 1990Google Scholar
  35. 35.
    Paralkar VM, Nandedkar AKN, Pointer RH, Battifora H, Weiss LM: Interaction of osteogenin, a heparin binding bone morphogenetic protein, with type IV collagen. J Biol Chem 28:17281–17284, 1990Google Scholar

Copyright information

© Plenum Publishing Corporation 1999

Authors and Affiliations

  • Yasuhiko Kiyozuka
  • Hiroaki Miyazaki
  • Katsuhiko Yoshizawa
  • Hideto Senzaki
  • Daigo Yamamoto
  • Kyoichi Inoue
  • Kazuhisa Bessho
  • Yasunori Okubo
  • Kenji Kusumoto
  • Airo Tsubura

There are no affiliations available

Personalised recommendations