Bulletin of Experimental Biology and Medicine

, Volume 136, Issue 2, pp 150–154 | Cite as

Role of Aqueous Medium in Mechanisms Underlying the Influence of Immunoactive Peptides in Ultralow Doses

  • E. I. Grigor'ev
  • V. Kh. Khavinson
  • V. V. Malinin
  • A. E. Grigor'ev
  • T. A. Kudryavtseva
Article

Abstract

The mechanism underlying the influence of peptides in ultralow doses is based on distant signal transduction from the ligand molecules to target cells by means of water solitons. Biological activity of synthetic immunoactive peptides in concentrations below 10-18 M depends on their structural and conformational characteristics. The data on temperature dependencies of the near-infrared spectrum for solutions of these peptides are presented.

ultralow doses peptides signal transduction solitons infrared spectroscopy 

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Copyright information

© Plenum Publishing Corporation 2003

Authors and Affiliations

  • E. I. Grigor'ev
    • 1
  • V. Kh. Khavinson
    • 1
  • V. V. Malinin
    • 1
  • A. E. Grigor'ev
    • 1
  • T. A. Kudryavtseva
    • 1
  1. 1.Northwestern Division of the Russian Academy of Medical SciencesSt. Petersburg Institute of Bioregulation and GerontologyRussia

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