Fed-batch fermentation of Lactobacillus lactis for hyper-production of l-lactic acid
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A fed-batch fermentation of Lactobacillus lactis to produce l-lactic acid was developed in which the residual glucose concentration in the culture was used to control a continuous feeding strategy. Up to 210 g l-lactic acid l−1 (97% yield) was obtained. The maximal dry cell was 2.7 g l−1 and the average l-lactic acid productivity was 2.2 g l−1 h−1.
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