Molecular Biology

, Volume 37, Issue 4, pp 571–584 | Cite as

Identification of Horizontal Gene Transfer from Phylogenetic Gene Trees

  • V. V. V'yugin
  • M. S. Gelfand
  • V. A. Lyubetsky


We suggest a new procedure to search for the genes with horizontal transfer events in their evolutionary history. The search is based on analysis of topology difference between the phylogenetic trees of gene (protein) groups and the corresponding phylogenetic species trees. Numeric values are introduced to measure the discrepancy between the trees. This approach was applied to analyze 40 prokaryotic genomes classified into 132 classes of orthologs. This resulted in a list of the candidate genes for which the hypothesis of horizontal transfer in evolution looks true.

horizontal gene transfer evolutionary event statistics of evolutionary event search phylogenetic species tree phylogenetic protein tree tree reconciliation 


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Copyright information

© MAIK “Nauka/Interperiodica” 2003

Authors and Affiliations

  • V. V. V'yugin
    • 1
  • M. S. Gelfand
    • 2
  • V. A. Lyubetsky
    • 1
  1. 1.Institute for Information Transmission ProblemsRussian Academy of SciencesMoscowRussia
  2. 2.State Research Center GosNIIGenetikaMoscowRussia

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