Biomedical Microdevices

, Volume 5, Issue 1, pp 55–60

An AC Magnetohydrodynamic Microfluidic Switch for Micro Total Analysis Systems

  • Asuncion V. Lemoff
  • Abraham P. Lee
Article

DOI: 10.1023/A:1024415400633

Cite this article as:
Lemoff, A.V. & Lee, A.P. Biomedical Microdevices (2003) 5: 55. doi:10.1023/A:1024415400633

Abstract

In this paper, a magnetohydrodynamic (MHD) microfluidic switch, which could form the basis for general microfluidic circuits, is reported. The switch uses an AC MHD pumping mechanism in which the Lorentz force is used to pump electrolytic solutions. By integrating two AC MHD pumps into different arms of a Y-shaped fluidic circuit, flow can be switched between the two arms by activating one of the micropumps and setting the other one at a counteracting pressure to prevent flow. Flow could be switched from one microchannel to another at a velocity of 0.3 mm/sec. This type of switch is easily integrated with other biochips and can be used to produce complex fluidic routing, which may have multiple applications in micro total analysis systems (μTAS). Examples of applications include on-chip combinatorial chemistry for drug discovery and drug testing, connectors for routing samples to different detectors, and general reconfigurable assays.

microfluidic switch micro total analysis system micropump magnetohydrodynamic (MHD) microfluidic circuit 

Copyright information

© Kluwer Academic Publishers 2003

Authors and Affiliations

  • Asuncion V. Lemoff
    • 1
  • Abraham P. Lee
    • 1
  1. 1.Department of Biomedical EngineeringUniversity of CaliforniaIrvine

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