, Volume 118, Issue 2, pp 117–121

The Emergence of a Synthetic Theory of Intron Evolution

  • Sandro J. de Souza

DOI: 10.1023/A:1024193323397

Cite this article as:
de Souza, S.J. Genetica (2003) 118: 117. doi:10.1023/A:1024193323397


The debate on the origin and evolution of the intron/exon structure of eukaryotic genes has witnessed profound changes in the last 10 years. Concepts from both the introns-early and introns-late theories have merged into a new synthetic theory of intron evolution. Here I review the debate and discuss the perspectives for the future.

intron evolution introns-early introns-late module 

Copyright information

© Kluwer Academic Publishers 2003

Authors and Affiliations

  • Sandro J. de Souza
    • 1
  1. 1.Ludwig Institute for Cancer Research, Sao Paulo BranchSao PauloBrazil

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