Breast Cancer Research and Treatment

, Volume 79, Issue 1, pp 129–131

E1AF Expression Levels are not Associated with Prognosis in Human Breast Cancer

  • Paul N. Span
  • Peggy Manders
  • Joop J.T.M. Heuvel
  • Louk V.A.M. Beex
  • C.G.J. (Fred) Sweep
Article

DOI: 10.1023/A:1023338424677

Cite this article as:
Span, P.N., Manders, P., Heuvel, J.J. et al. Breast Cancer Res Treat (2003) 79: 129. doi:10.1023/A:1023338424677

Abstract

E1AF is a transcription factor involved in regulation of several metastasis-associated genes, and is associated with overexpression of HER2/neu. We were unable to find a clear prognostic value of E1AF expression in human breast cancer. Furthermore, no association of E1AF levels with HER2/neu mRNA levels, hormone receptor status, histological grade, tumor size, or lymph node involvement was found.

breast neoplasm HER2/neu matrix-metalloproteinases prognosticator quantitative real-time RT-PCR survival analysis 

Copyright information

© Kluwer Academic Publishers 2003

Authors and Affiliations

  • Paul N. Span
    • 1
  • Peggy Manders
    • 1
    • 2
  • Joop J.T.M. Heuvel
    • 1
  • Louk V.A.M. Beex
    • 2
  • C.G.J. (Fred) Sweep
    • 1
  1. 1.Department of Chemical EndocrinologyUniversity Medical Center NijmegenNijmegenThe Netherlands
  2. 2.Department of Medical OncologyUniversity Medical Center NijmegenNijmegenThe Netherlands

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