Journal of Clinical Immunology

, Volume 18, Issue 2, pp 161–166

Primary Immunodeficiency Diseases in Latin America: First Report from Eight Countries Participating in the LAGID

  • Marta Zelazko
  • Magda Carneiro-Sampaio
  • Monica Cornejo De Luigi
  • Diana Garcia De Olarte
  • Oscar Porras Madrigal
  • Renato Berrón Perez
  • Agueda Cabello
  • Marylin Valentin Rostan
  • Ricardo U. Sorensen
Article

Abstract

The Latin American Group for Primary Immunodeficiencies, formed in 1993, presently includes 12 countries. One goal was to study the frequency of primary immunodeficiencies in various regions of the American continent and to enhance knowledge about these diseases among primary-care physicians, as well as allergist–immunologists. Important for this purpose was the development of a registry of primary immunodeficiencies using a uniform questionnaire and computerized database. To date, eight countries have collected information on a total of 1428 patients. Predominantly antibody deficiencies were reported in 58% of patients, followed by cellular and antibody immunodeficiencies associated with other abnormalities in 18%, immunodeficiency syndromes associated with granulocyte dysfunction in 8%, phagocytic disorders in 9%, combined cellular and antibody immunodeficiencies in 5%, and complement deficiencies in 2% of patients. The information gathered from this initial analysis of data will serve to expand the patient database to more areas within participating countries and to new countries and to increase collaboration toward better diagnosis and treatment of these diseases.

Primary immunodeficiencies registry Latin America 

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Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • Marta Zelazko
    • 1
  • Magda Carneiro-Sampaio
    • 2
  • Monica Cornejo De Luigi
    • 3
  • Diana Garcia De Olarte
    • 4
  • Oscar Porras Madrigal
    • 5
  • Renato Berrón Perez
    • 6
  • Agueda Cabello
    • 7
  • Marylin Valentin Rostan
    • 8
  • Ricardo U. Sorensen
    • 9
  1. 1.National Pediatric Hospital Juan P. GarrahanBuenos AiresArgentina
  2. 2.Institute of Biomedical SciencesUniversity of São PauloSão PauloBrazil
  3. 3.University of ValparaisoValparaisoChile
  4. 4.University of AntioquiaMedellinColombia
  5. 5.Immunology ServiceNational Children's Hospital Dr. Carlos Saenz HerreraSan JoseCosta Rica
  6. 6.Immunology ServiceNational Institute of PediatricsMexico CityMexico
  7. 7.Institute for Health Science ResearchNational University of Rio dela Plata and LagerenzaAsunciónParaguay
  8. 8.Pigalle ClinicMontevideoUruguay
  9. 9.Department of PediatricsLSU Medical CenterNew Orleans

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